Effect Of Estrogen Replacement And Calcitonin Therapies On Bone Around Titanium Implants Placed In Ovariectomized Rats: A Histometric Study.

dc.creatorNociti, Francisco Humberto
dc.creatorSallum, Antonio Wilson
dc.creatorSallum, Enilson Antonio
dc.creatorDuarte, Poliana Mendes
dc.date
dc.date2015-11-27T12:49:26Z
dc.date2015-11-27T12:49:26Z
dc.date.accessioned2018-03-29T00:56:50Z
dc.date.available2018-03-29T00:56:50Z
dc.identifierThe International Journal Of Oral & Maxillofacial Implants. v. 17, n. 6, p. 786-92
dc.identifier0882-2786
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/12507237
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195229
dc.identifier12507237
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295462
dc.descriptionThe aim of the present study was to evaluate whether hormone replacement therapy (HRT) and calcitonin (CT) administration could influence bone healing around implants placed in ovariectomized (OVX) rats. One screw-type titanium implant was placed bilaterally in OVX rats. The animals were assigned to one of the following groups: group 1 (n = 15), sham surgeries; group 2 (n = 15), OVX rats; group 3 (n = 14), OVX rats administered CT 4 days/week (16 IU/kg); group 4 (n = 14), OVX rats administered 17beta estradiol daily (20 microg/kg). After 60 days, the animals were sacrificed and undecalcified sections obtained. Bone-to-implant contact (BIC) and bone area (BA) around the implants were determined separately for the cortical (zone A) and cancellous (zone B) bone areas. In zone A, intergroup analysis did not reveal a significant difference regarding BIC. In contrast, the HRT group (group 4) presented greater BA than groups 2 and 3 (P < .05). Data from zone B revealed that HRT eliminated the negative effect of the ovariectomy on BIC and BA (P < .05), while CT had no effect (P > .05). It was the first study to evaluate and demonstrate the impact of HRT and CT on bone around titanium implants in an estrogen-deficient model. Within the limits of the present study, it may be concluded that HRT may prevent the influence that estrogen deficiency exerts on bone healing around titanium implants.
dc.description17
dc.description786-92
dc.languageeng
dc.relationThe International Journal Of Oral & Maxillofacial Implants
dc.relationInt J Oral Maxillofac Implants
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnalysis Of Variance
dc.subjectAnimals
dc.subjectBone Regeneration
dc.subjectCalcitonin
dc.subjectDental Implants
dc.subjectEstradiol
dc.subjectEstrogen Replacement Therapy
dc.subjectEstrogens
dc.subjectFemale
dc.subjectImplants, Experimental
dc.subjectModels, Animal
dc.subjectOsseointegration
dc.subjectOvariectomy
dc.subjectOvary
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectStatistics, Nonparametric
dc.subjectTibia
dc.subjectTitanium
dc.subjectWound Healing
dc.titleEffect Of Estrogen Replacement And Calcitonin Therapies On Bone Around Titanium Implants Placed In Ovariectomized Rats: A Histometric Study.
dc.typeArtículos de revistas


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