Effects Of Chlorella Vulgaris Extract On Cytokines Production In Listeria Monocytogenes Infected Mice.

dc.creatorQueiroz, Mary L S
dc.creatorBincoletto, Claudia
dc.creatorValadares, Marize C
dc.creatorDantas, Denise C M
dc.creatorSantos, Leonilda M B
dc.date2002-Aug
dc.date2015-11-27T12:49:20Z
dc.date2015-11-27T12:49:20Z
dc.date.accessioned2018-03-29T00:56:36Z
dc.date.available2018-03-29T00:56:36Z
dc.identifierImmunopharmacology And Immunotoxicology. v. 24, n. 3, p. 483-96, 2002-Aug.
dc.identifier0892-3973
dc.identifier10.1081/IPH-120014731
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/12375742
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/195165
dc.identifier12375742
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295398
dc.descriptionIn this study, we have investigated the effects of the unicellular-green-algae Chlorella vulgaris on the production of INF-gamma, IL-2, IL-4 and IL-10 in normal and Listeria monocytogenes infected mice. Our results demonstrated that in normal/non infected mice, CVE administration produced no effects in the levels of all cytokines studied. However, Listeria monocytogenes infection enhanced the production of INF-gamma and IL-2 at 48 and 72 h after the bacteria inoculation. Interestingly, the treatment with five consecutive doses of 50 mg/Kg/day of Chlorella vulgaris given previously to infection, led to further increases in INF-gamma and IL-2 levels at 48 and 72 h in relation to the presence of infection alone. No changes in IL-4 and IL-10 production were observed in Listeria monocytogenes and CVE treated/infected mice. These results are in accordance with the literature, which shows that CVE is a biological response modifier that enhances resistance to Listeria monocytogenes through augmentation of IL-2 and IFN-gamma.
dc.description24
dc.description483-96
dc.languageeng
dc.relationImmunopharmacology And Immunotoxicology
dc.relationImmunopharmacol Immunotoxicol
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectChlorella
dc.subjectCytokines
dc.subjectImmunologic Factors
dc.subjectInterferon-gamma
dc.subjectInterleukin-10
dc.subjectInterleukin-12
dc.subjectInterleukin-4
dc.subjectListeriosis
dc.subjectMale
dc.subjectMice
dc.subjectMice, Inbred Balb C
dc.titleEffects Of Chlorella Vulgaris Extract On Cytokines Production In Listeria Monocytogenes Infected Mice.
dc.typeArtículos de revistas


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