Effects Of The Green Algae Chlorella Vulgaris On The Response Of The Host Hematopoietic System To Intraperitoneal Ehrlich Ascites Tumor Transplantation In Mice.

dc.creatorJusto, G Z
dc.creatorSilva, M R
dc.creatorQueiroz, M L
dc.date2001-Feb
dc.date2015-11-27T12:29:15Z
dc.date2015-11-27T12:29:15Z
dc.date.accessioned2018-03-29T00:55:54Z
dc.date.available2018-03-29T00:55:54Z
dc.identifierImmunopharmacology And Immunotoxicology. v. 23, n. 1, p. 119-32, 2001-Feb.
dc.identifier0892-3973
dc.identifier10.1081/IPH-100102573
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/11322644
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194986
dc.identifier11322644
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295219
dc.descriptionChlorella vulgaris extract (CVE) was examined for its effects on the Ehrlich ascites tumor-induced suppression in the numbers of bone marrow and spleen granulocyte-macrophage progenitor cells (CFU-GM) in mice. No effects on bone marrow and spleen CFU-GM, as compared to controls, were observed in normal mice given 50, 100 and 200 mg/kg CVE orally for 5 days. In tumor-bearing mice, myelosuppression concomitant with increased number of spleen CFU-GM were observed. The number of CFU-GM in the bone marrow was restored to control levels after the administration of CVE (50, 100 and 200 mg/kg) to tumor-bearing mice, and a slight reduction in spleen colony formation was observed in these animals. In addition, CVE significantly prolonged the survival of mice inoculated with the Ehrlich ascites tumor. These results suggest a protective antitumor effect of CVE which might be attributable, at least in part, to the stimulation of the production and, possibly, maturation of granulocytes and macrophages.
dc.description23
dc.description119-32
dc.languageeng
dc.relationImmunopharmacology And Immunotoxicology
dc.relationImmunopharmacol Immunotoxicol
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdministration, Oral
dc.subjectAnimals
dc.subjectBone Marrow Cells
dc.subjectCarcinoma, Ehrlich Tumor
dc.subjectCells, Cultured
dc.subjectChlorella
dc.subjectColony-forming Units Assay
dc.subjectGerm-free Life
dc.subjectGranulocyte-macrophage Colony-stimulating Factor
dc.subjectHematopoiesis, Extramedullary
dc.subjectHematopoietic Stem Cells
dc.subjectInjections, Intraperitoneal
dc.subjectLeukopoiesis
dc.subjectMale
dc.subjectMice
dc.subjectMice, Inbred Balb C
dc.subjectNeoplasm Transplantation
dc.subjectPlant Extracts
dc.subjectRecombinant Proteins
dc.subjectSpleen
dc.subjectSurvival Rate
dc.titleEffects Of The Green Algae Chlorella Vulgaris On The Response Of The Host Hematopoietic System To Intraperitoneal Ehrlich Ascites Tumor Transplantation In Mice.
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución