dc.creatorBóscolo, F N
dc.creatorde Almeida, S M
dc.creatorCury, J A
dc.creatorLourenço, R M
dc.date
dc.date2015-11-27T12:29:03Z
dc.date2015-11-27T12:29:03Z
dc.date.accessioned2018-03-29T00:55:30Z
dc.date.available2018-03-29T00:55:30Z
dc.identifierPesquisa Odontológica Brasileira = Brazilian Oral Research. v. 15, n. 3, p. 223-8
dc.identifier1517-7491
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/11705270
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194883
dc.identifier11705270
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1295116
dc.descriptionThe present study evaluated the effect of low doses of electron radiation on the activity of phosphodiesterases in granulation tissue. In order to induce growth of granulation tissue, a PVC sponge disk was introduced under the dorsal skin of 84 Wistar rats. The rats were divided in two groups, control and irradiated. The enzymatic activity was evaluated according to the evolution of the granulation tissue after 5, 7, 10, 14, 17, 20 and 24 days. Irradiation was carried out 3 days after the implantation of the sponge, by means of a linear accelerator, with energy of 6 MeV, and dose of 1.0 Gy. The results of this study showed that 5'-nucleotidase and ATPase had their activity directly affected by irradiation only in the beginning of the tissue repairing process. Alkaline phosphatase did not suffer any direct effect of irradiation. It is possible that the main factor has been the damage of the cellular components responsible for the growth of granulation tissue, which determine the production of enzymes according to the necessity.
dc.description15
dc.description223-8
dc.languagepor
dc.relationPesquisa Odontológica Brasileira = Brazilian Oral Research
dc.relationPesqui Odontol Bras
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAnimals
dc.subjectBeta Particles
dc.subjectGranulation Tissue
dc.subjectMale
dc.subjectPhosphoric Diester Hydrolases
dc.subjectRats
dc.subjectRats, Wistar
dc.title[activity Of Phosphodiesterases In Granulation Tissue Treated With Electron Irradiation -- Experimental Study On Rats].
dc.typeArtículos de revistas


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