dc.creatorMontenegro, M A
dc.creatorScotoni, A E
dc.creatorCendes, F
dc.date1999-Jun
dc.date2015-11-27T12:19:39Z
dc.date2015-11-27T12:19:39Z
dc.date.accessioned2018-03-29T00:53:38Z
dc.date.available2018-03-29T00:53:38Z
dc.identifierArquivos De Neuro-psiquiatria. v. 57, n. 2B, p. 356-60, 1999-Jun.
dc.identifier0004-282X
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/10450338
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194398
dc.identifier10450338
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1294631
dc.descriptionPhenytoin is an effective antiepileptic drug, although, it can be associated with many side effects, including dyskinesia. To describe the clinical characteristics of phenytoin induced dyskinesia. We investigated the occurrence of involuntary movements in patients followed at our adult and pediatric epilepsy clinics during the period of one year. Three patients presented with phenytoin-induced dyskinesia: one adult with axial and orofacial dyskinesia, and two children with choreoathetosis. They did not have other signs of phenytoin intoxication and had complete recovery after phenytoin withdrawal. Phenytoin induced dyskinesia may occur during either chronic or initial treatment and with normal serum phenytoin levels. However, it occurs most often in patients on polytherapy, usually after increasing dosage and with toxic serum levels. Other signs of phenytoin intoxication may be present in these patients, but often the dyskinesia is the only side effect, which may delay the diagnosis and treatment. The clinical characteristics of the involuntary movements vary and may be focal or generalized, most often characterized by choreoathetosis and dyskinesias. These may last for hours, days or even years, but frequently disappear completely after phenytoin withdrawal.
dc.description57
dc.description356-60
dc.languageeng
dc.relationArquivos De Neuro-psiquiatria
dc.relationArq Neuropsiquiatr
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAnticonvulsants
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectDyskinesia, Drug-induced
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPhenytoin
dc.titleDyskinesia Induced By Phenytoin.
dc.typeArtículos de revistas


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