Fatty Acid-mediated Uncoupling Of Potato Tuber Mitochondria.

dc.creatorSaviani, E E
dc.creatorMartins, I S
dc.date1998-Apr
dc.date2015-11-27T12:19:12Z
dc.date2015-11-27T12:19:12Z
dc.date.accessioned2018-03-29T00:52:43Z
dc.date.available2018-03-29T00:52:43Z
dc.identifierBiochemistry And Molecular Biology International. v. 44, n. 4, p. 833-9, 1998-Apr.
dc.identifier1039-9712
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/9584997
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194159
dc.identifier9584997
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1294392
dc.descriptionThe present work examined whether the ATP/ADP carrier, other than the plant uncoupling mitochondrial protein, participates in free fatty acid-mediated uncoupling of potato tuber mitochondria. The basal respiration rate of succinate-energized mitochondria was stimulated by a low concentration of palmitate (20 microM). This uncoupling was reversed by 10 microM carboxyatractyloside and by the subsequent addition of 0.1% bovine serum albumin. The decrease in membrane potential caused by palmitate was suppressed by carboxyatractyloside (1 microM) and, to a lesser degree, by bongkrekate (20 microM). GTP could also reversed this decrease via a carboxyatractyloside-independent mechanism. These results indicate that the ATP/ADP carrier, along with the plant uncoupling mitochondrial protein, participates in the protonophoric action of palmitate in potato tuber mitochondria.
dc.description44
dc.description833-9
dc.languageeng
dc.relationBiochemistry And Molecular Biology International
dc.relationBiochem. Mol. Biol. Int.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAtractyloside
dc.subjectCarrier Proteins
dc.subjectFatty Acids, Nonesterified
dc.subjectIntracellular Membranes
dc.subjectIon Channels
dc.subjectMembrane Potentials
dc.subjectMembrane Proteins
dc.subjectMitochondria
dc.subjectMitochondrial Proteins
dc.subjectOxygen Consumption
dc.subjectPalmitates
dc.subjectPlant Proteins
dc.subjectReceptors, Cytoplasmic And Nuclear
dc.subjectSerum Albumin, Bovine
dc.subjectSolanum Tuberosum
dc.subjectSuccinates
dc.titleFatty Acid-mediated Uncoupling Of Potato Tuber Mitochondria.
dc.typeArtículos de revistas


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