T Lymphocytes In Mercury-exposed Workers.

dc.creatorQueiroz, M L
dc.creatorDantas, D C
dc.date1997-Nov
dc.date2015-11-27T12:19:03Z
dc.date2015-11-27T12:19:03Z
dc.date.accessioned2018-03-29T00:52:26Z
dc.date.available2018-03-29T00:52:26Z
dc.identifierImmunopharmacology And Immunotoxicology. v. 19, n. 4, p. 499-510, 1997-Nov.
dc.identifier0892-3973
dc.identifier10.3109/08923979709007671
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/9436049
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/194082
dc.identifier9436049
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1294315
dc.descriptionIn this work we have investigated the changes in T-helper and T-suppressor cells and T-cell proliferative response to phytohemagglutinin (PHA) in mercury-exposed workers. The study group consisted of 33 workers from a mercury-producing plant with a mean age of 29 years and a mean exposure period of 19 months. At the time of testing, and for the three previous months, the exposed population had urinary mercury levels below the currently accepted limit of 50 micrograms/g creatinine. A reverse CD4+/CD8+ ratio was observed in the mercury-exposed individuals which was characterized by a reduction in the number of CD4+ lymphocytes. No changes were observed in the proliferative response of lymphocytes from exposed individuals to PHA. Similarly, no proliferative response was observed when lymphocytes from normal individuals were cultivated in the presence of serum from the exposed workers. We found no correlations between lymphocytes changes and urinary mercury concentrations, time of exposure or the age of the workers.
dc.description19
dc.description499-510
dc.languageeng
dc.relationImmunopharmacology And Immunotoxicology
dc.relationImmunopharmacol Immunotoxicol
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectCd4-cd8 Ratio
dc.subjectCd4-positive T-lymphocytes
dc.subjectHumans
dc.subjectLymphocyte Activation
dc.subjectMale
dc.subjectMercury
dc.subjectOccupational Exposure
dc.subjectPhytohemagglutinins
dc.subjectT-lymphocytes, Helper-inducer
dc.subjectT-lymphocytes, Regulatory
dc.titleT Lymphocytes In Mercury-exposed Workers.
dc.typeArtículos de revistas


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