Biosynthesis Of A Trypanocide By Chromobacterium Violaceum.

dc.creatorDurán, N
dc.creatorAntonio, R V
dc.creatorHaun, M
dc.creatorPilli, R A
dc.date1994-Nov
dc.date2015-11-27T12:18:32Z
dc.date2015-11-27T12:18:32Z
dc.date.accessioned2018-03-29T00:51:21Z
dc.date.available2018-03-29T00:51:21Z
dc.identifierWorld Journal Of Microbiology & Biotechnology. v. 10, n. 6, p. 686-90, 1994-Nov.
dc.identifier0959-3993
dc.identifier10.1007/BF00327960
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/24421196
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/193801
dc.identifier24421196
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1294034
dc.descriptionRadio-isotope studies indicated not only that L-tryptophan can serve as carbon source for synthesis of the trypanocide, violacein by Chromobacterium violaceum (BB-78 strain) but also that isatin and indole 3-acetic acid are both important metabolic intermediates. Using 3-indolyl [2-(14)C] and [1-(14)C] acetic acid, it was found that the carboxylic carbon was not eliminated and that indole-3-acetic acid was incorporated intact into the pigment structure. N-Ethyl(5-hydroxy-indol-3-yl)-2-indolylethylamide is also an important metabolic intermediate in the violacein biosynthesis. This is the first report of a metabolic scheme for violacein synthesis which includes an intermediate other than L-tryptophan.
dc.description10
dc.description686-90
dc.languageeng
dc.relationWorld Journal Of Microbiology & Biotechnology
dc.relationWorld J. Microbiol. Biotechnol.
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.titleBiosynthesis Of A Trypanocide By Chromobacterium Violaceum.
dc.typeArtículos de revistas


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