Pharmacokinetic Profile Of Two Different Pharmaceutical Forms Of Theophylline (a Slow Release Tablet And A Syrup) After Multiple Dose Administration To Healthy Human Volunteers.

dc.creatorMuscará, M N
dc.creatorHofstätter, E A
dc.creatorde Nucci, G
dc.date
dc.date2015-11-27T12:18:20Z
dc.date2015-11-27T12:18:20Z
dc.date.accessioned2018-03-29T00:50:58Z
dc.date.available2018-03-29T00:50:58Z
dc.identifierMemórias Do Instituto Oswaldo Cruz. v. 88, n. 1, p. 155-8
dc.identifier0074-0276
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/8246751
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/193705
dc.identifier8246751
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293938
dc.descriptionDue to the narrow therapeutic range of theophylline, plasma concentrations of this drug are monitored in patients undergoing chronic therapy. Slow-release preparations avoid the fluctuations in plasma levels and improve patient compliance. In this study, we have compared the pharmacokinetic profiles of a theophylline slow-release tablet and a syrup form, when administered in multiple doses to healthy adult volunteers. The classification based upon releasing patterns is confirmed.
dc.description88
dc.description155-8
dc.languageeng
dc.relationMemórias Do Instituto Oswaldo Cruz
dc.relationMem. Inst. Oswaldo Cruz
dc.rightsaberto
dc.rights
dc.sourcePubMed
dc.subjectAdult
dc.subjectDelayed-action Preparations
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectTheophylline
dc.titlePharmacokinetic Profile Of Two Different Pharmaceutical Forms Of Theophylline (a Slow Release Tablet And A Syrup) After Multiple Dose Administration To Healthy Human Volunteers.
dc.typeArtículos de revistas


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