Alterations To The Permeability Of Plant And Animal Mitochondria Submitted To Ca2+ Releasing Agents.

dc.creatorMorselli, A L
dc.creatorPereira-Da-Silva, L
dc.date1992-Nov
dc.date2015-11-27T12:18:12Z
dc.date2015-11-27T12:18:12Z
dc.date.accessioned2018-03-29T00:50:47Z
dc.date.available2018-03-29T00:50:47Z
dc.identifierComparative Biochemistry And Physiology. B, Comparative Biochemistry. v. 103, n. 3, p. 569-74, 1992-Nov.
dc.identifier0305-0491
dc.identifier
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/1458833
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/193656
dc.identifier1458833
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293889
dc.description1. Mitochondria from different rat tissues and from plants were compared as regards their sensitivity towards Ca2+ in the presence of different Ca2+ releasing agents, and the phospholipase A2 activity was evaluated in the different mitochondrial preparations. 2. The mitochondria were exposed to Ca2+ and an oxidant such as t-butylhydroperoxide or diamide or to Ca2+ and inorganic phosphate, and plant mitochondria were seen to be much more resistant than liver, brain or kidney mitochondria of rats to the deleterious effects of these agents. 3. The phospholipase A2 activity is not directly involved in the alterations of the mitochondrial inner membrane permeability within the first 10 min of incubation under our experimental conditions. 4. The protection conferred by ATP and Mg2+ against Ca2+ efflux from mitochondria or the decrease in the mitochondrial transmembrane electrical potential was also observed under our experimental conditions, but cannot be attributed to an enhancement of the reacylation of lysophospholipids resulting from the phospholipase A2 activity.
dc.description103
dc.description569-74
dc.languageeng
dc.relationComparative Biochemistry And Physiology. B, Comparative Biochemistry
dc.relationComp. Biochem. Physiol., B
dc.rightsfechado
dc.rights
dc.sourcePubMed
dc.subjectAdenosine Triphosphate
dc.subjectAnimals
dc.subjectCalcium
dc.subjectDiamide
dc.subjectFemale
dc.subjectIn Vitro Techniques
dc.subjectMagnesium
dc.subjectMembrane Potentials
dc.subjectMitochondria
dc.subjectPermeability
dc.subjectPeroxides
dc.subjectPhosphates
dc.subjectPhospholipases A
dc.subjectPhospholipases A2
dc.subjectPlants
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectSpecies Specificity
dc.subjectTert-butylhydroperoxide
dc.titleAlterations To The Permeability Of Plant And Animal Mitochondria Submitted To Ca2+ Releasing Agents.
dc.typeArtículos de revistas


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