The electrocatalytic activity of a supramolecular assembly of CoTsPc/FeT4MPyP on multi-walled carbon nanotubes towards L-glutathione, and its determination in human erythrocytes

dc.creatorLuz, RCS
dc.creatorMaroneze, CM
dc.creatorTanaka, AA
dc.creatorKubota, LT
dc.creatorGushikem, Y
dc.creatorDamos, FS
dc.date2010
dc.dateOCT
dc.date2014-11-20T00:19:54Z
dc.date2015-11-26T18:08:00Z
dc.date2014-11-20T00:19:54Z
dc.date2015-11-26T18:08:00Z
dc.date.accessioned2018-03-29T00:50:07Z
dc.date.available2018-03-29T00:50:07Z
dc.identifierMicrochimica Acta. Springer Wien, v. 171, n. 41671, n. 169, n. 178, 2010.
dc.identifier0026-3672
dc.identifierWOS:000281669900023
dc.identifier10.1007/s00604-010-0417-y
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/73869
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/73869
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/73869
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293722
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionThe electrocatalytic activity of a supramolecular complex based on cobalt(II) phthalocyanine tetrasulfonate and iron(III) tetra-(N-methyl-4-pyridyl)-porphyrin adsorbed on multi-walled carbon nanotubes for the oxidation of L-glutathione (GSH) was investigated at pH 7.4. Scanning electron microscopy and energy dispersive X-ray spectrometry were used to characterize the morphologies and composition of the materials. The modified electrode displayed efficient electrocatalytic activity in terms of oxidation of GSH at an oxidation potential of 0 V (versus Ag/AgCl). Cyclic voltammetry and amperometry indicated that the oxidation involves 2-electrons, with a heterogeneous rate constant of 4.9 x 10(5) mol(-1) L s(-1). The response is linear from 2 to 210 mu mol L(-1), the sensitivity is 1570 mu A L mmol(-1), the detection limit is 0.03 mu mol L(-1), and the relative standard deviation of 110 mu mol L(-1) GSH was 2.6% (n=10). The modified electrode was applied to the determination of GSH in erythrocytes and the results were in agreement with those obtained by a method reported in the literature.
dc.description171
dc.description41671
dc.description169
dc.description178
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageen
dc.publisherSpringer Wien
dc.publisherWien
dc.publisherAustria
dc.relationMicrochimica Acta
dc.relationMicrochim. Acta
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectReduced L-glutathione
dc.subjectSupramolecular assembly, Cobalt (II) tetrasulphonated phthalocyanine
dc.subjectIron (III) tetra-(N-methyl-4-pyridyl)-porphyrin
dc.subjectMulti-walled carbon nanotubes
dc.subjectErythrocytes
dc.subjectPyrolytic-graphite Electrode
dc.subjectReduced Glutathione
dc.subjectAscorbic-acid
dc.subjectOxidation
dc.subjectDerivatives
dc.subjectBiosensor
dc.subjectPowder
dc.subjectThiols
dc.subjectMicroelectrode
dc.subjectSystem
dc.titleThe electrocatalytic activity of a supramolecular assembly of CoTsPc/FeT4MPyP on multi-walled carbon nanotubes towards L-glutathione, and its determination in human erythrocytes
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución