Interference of dexamethasone in the pulmonary cycle of Strongyloides venezuelensis in rats

dc.creatorTefe-Silva, C
dc.creatorSouza, DI
dc.creatorUeta, MT
dc.creatorFloriano, EM
dc.creatorFaccioli, LH
dc.creatorRamos, SG
dc.date2008
dc.dateOCT
dc.date2014-07-30T14:33:56Z
dc.date2015-11-26T18:06:52Z
dc.date2014-07-30T14:33:56Z
dc.date2015-11-26T18:06:52Z
dc.date.accessioned2018-03-29T00:49:00Z
dc.date.available2018-03-29T00:49:00Z
dc.identifierAmerican Journal Of Tropical Medicine And Hygiene. Amer Soc Trop Med & Hygiene, v. 79, n. 4, n. 571, n. 578, 2008.
dc.identifier0002-9637
dc.identifierWOS:000259858000017
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/60426
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/60426
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293453
dc.descriptionThe aim of this study was to investigate the interference of a daily treatment of dexamethasone in the pulmonary cycle of Strongyloides venezuelensis infection in rats. Three principal effects were found: 1) increased alveolar hemorrhagic inflammation provoked by the passage of larvae into alveolar spaces; 2) significant decrease of eosinophil and mast cell migration to the axial septum of the lungs; and 3) impaired formation of the reticular fiber network, interfering with granuloma organization. This study showed that the use of drugs with immunomodulatory actions, such as dexamethasone, in addition to interfering with the morbidity from the pulmonary cycle of S. venezuelensis infection, may contribute to showing the mechanisms involved in its pathogenesis.
dc.descriptiono TEXTO COMPLETO DESTE ARTIGO, ESTARÁ DISPONÍVEL À PARTIR DE AGOSTO DE 2015.
dc.description79
dc.description4
dc.description571
dc.description578
dc.languageen
dc.publisherAmer Soc Trop Med & Hygiene
dc.publisherMclean
dc.publisherEUA
dc.relationAmerican Journal Of Tropical Medicine And Hygiene
dc.relationAm. J. Trop. Med. Hyg.
dc.rightsembargo
dc.sourceWeb of Science
dc.subjectEndothelial Growth-factor
dc.subjectHuman Eosinophils
dc.subjectAirway Hyperresponsiveness
dc.subjectGastrointestinal-tract
dc.subjectStercoralis Infection
dc.subjectAsthmatic Airways
dc.subjectGene-expression
dc.subjectIn-vitro
dc.subjectTgf-beta
dc.subjectInflammation
dc.titleInterference of dexamethasone in the pulmonary cycle of Strongyloides venezuelensis in rats
dc.typeArtículos de revistas


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