beta-catenin and E-cadherin expression in salivary gland tumors

dc.creatorFuruse, C
dc.creatorCury, PR
dc.creatorAltemani, A
dc.creatorPinto, DD
dc.creatorde Araujo, NS
dc.creatorde Araujo, VC
dc.date2006
dc.dateJUL
dc.date2014-11-19T23:06:54Z
dc.date2015-11-26T18:06:49Z
dc.date2014-11-19T23:06:54Z
dc.date2015-11-26T18:06:49Z
dc.date.accessioned2018-03-29T00:48:58Z
dc.date.available2018-03-29T00:48:58Z
dc.identifierInternational Journal Of Surgical Pathology. Sage Publications Inc, v. 14, n. 3, n. 212, n. 217, 2006.
dc.identifier1066-8969
dc.identifierWOS:000239776300005
dc.identifier10.1177/1066896906290652
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/55428
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/55428
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/55428
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293444
dc.descriptionThis study evaluated the expression of E-cadherin and beta-catenin in salivary gland tumors. Twelve biopsy specimens from cases diagnosed as pleomorphic adenoma, 17 adenoid cystic carcinomas, 10 epithelial-myoepithelial carcinomas, and 4 polymorphous low-grade adenocarcinomas were inummohistochemically labeled for E-cadherin and beta-catenin antibodies. Healthy salivary glands were used as controls. Membrane-associated E-cadherin and beta-catenin expression was present in all the tumor types studied. E-cadherin and beta-catenin showed a similar distribution; however, beta-catenin labeling was weaker than that for E-cadherin. In the epithelial-myoepithelial carcinomas, myoepithelial cells exhibited diffuse nuclear staining, although occasional cells presented only focal labeling. Epithelial-myoepithelial carcinomas present changes in beta-catenin expression but the other salivary tumors studied do not, which may reflect divergence in tumorigenesis of this extensive subset of salivary gland tumors.
dc.description14
dc.description3
dc.description212
dc.description217
dc.languageen
dc.publisherSage Publications Inc
dc.publisherThousand Oaks
dc.publisherEUA
dc.relationInternational Journal Of Surgical Pathology
dc.relationInt. J. Surg. Pathol.
dc.rightsfechado
dc.rightshttp://www.uk.sagepub.com/aboutus/openaccess.htm
dc.sourceWeb of Science
dc.subjectbeta-catenin
dc.subjectE-cadherin
dc.subjectsalivary gland tumor
dc.subjectCell-adhesion Molecules
dc.subjectEpithelial-myoepithelial Carcinoma
dc.subjectAdenoid Cystic Carcinoma
dc.subjectLymph-node Metastasis
dc.subjectColorectal-cancer
dc.subjectImmunohistochemical Expression
dc.subjectInverse Correlation
dc.subjectGastric Carcinomas
dc.subjectGene-mutations
dc.subjectBreast-cancer
dc.titlebeta-catenin and E-cadherin expression in salivary gland tumors
dc.typeArtículos de revistas


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