Effect of continuous and pulsed therapeutic ultrasound in the appearance of local recurrence of mammary cancer in rats

dc.creatorde Rezende, LF
dc.creatorda Costa, ECS
dc.creatorSchenka, NGM
dc.creatorSchenka, AA
dc.creatorUemura, G
dc.date2012
dc.dateJUL-SEP
dc.date2014-07-30T17:05:29Z
dc.date2015-11-26T18:06:26Z
dc.date2014-07-30T17:05:29Z
dc.date2015-11-26T18:06:26Z
dc.date.accessioned2018-03-29T00:48:37Z
dc.date.available2018-03-29T00:48:37Z
dc.identifierJournal Of Buon. Zerbinis Medical Publ, v. 17, n. 3, n. 581, n. 584, 2012.
dc.identifier1107-0625
dc.identifierWOS:000309793000029
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63830
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/63830
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293354
dc.descriptionPurpose: Ultrasound (US) therapy is an elect rot hermotherapeutic modality that uses US energy to provoke physical and chemical alterations. US therapy has been widely used in physical therapy. However in clinical practice, it is contra-indicated in cancer patients due to the possibility of exacerbating tumor growth. Methods: Sixty-eight female Sprague-Dawley rats bred in UNIFAE vivarium were studied. At 50 days of age, 7, 12-dimetylbenz(a)anthracene (7, 12-DMBA) was administered to 35 rats by gastric gavage to induce mammary cancer After 90 days the mammary glands of the rats belonging to the group with mammary cancer induction and stimulated by US were removed. Animals received either continuous or pulsed US. US waves were generated at a frequency of 1 MHz during 10 days, with an intensity dose of 0.5 W in the continuous group, and 0.9 W (duty cycle: 20%) in the pulsed group. Results: Among the rats treated with continuous US, 44.4% developed local recurrence, while among the rats treated with pulsed US, 22.2% had local tumor recurrence (p < 0.05). No evidence of distant metastases was shown in any of the rats studied. Conclusion: The use ofcontinuous and pulsed therapeutic US promoted the development of local recurrence of mammary cancer in female Sprague-Dawley rats in the postoperative period.
dc.description17
dc.description3
dc.description581
dc.description584
dc.descriptionPAPEC - Centro Universitario das Faculdades Associadas de Ensino - FAE, Sao Joao da Boa Vista, Sao Paulo, Brazil
dc.languageen
dc.publisherZerbinis Medical Publ
dc.publisherAthens
dc.publisherGrécia
dc.relationJournal Of Buon
dc.relationJ. BUON
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectbreast cancer
dc.subjectbreast cancer recurrence
dc.subjecttherapeutic ultrasound
dc.subjectphysical therapy
dc.subject20-year Follow-up
dc.subjectBreast-cancer
dc.subjectRadical-mastectomy
dc.subjectIrradiation
dc.titleEffect of continuous and pulsed therapeutic ultrasound in the appearance of local recurrence of mammary cancer in rats
dc.typeArtículos de revistas


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