EXTENDED-SPECTRUM BETA-LACTAMASES AMONG Enterobacteriaceae ISOLATED IN A PUBLIC HOSPITAL IN BRAZIL

dc.creatorDropa, M
dc.creatorBalsalobre, LC
dc.creatorLincopan, N
dc.creatorMamizuka, EM
dc.creatorMurakami, T
dc.creatorCassettari, VC
dc.creatorFranco, F
dc.creatorGuida, SM
dc.creatorBalabakis, AJ
dc.creatorPassadore, LF
dc.creatorSantos, SR
dc.creatorMatte, GR
dc.creatorMatte, MH
dc.date2009
dc.dateJUL-AUG
dc.date2014-07-30T17:34:08Z
dc.date2015-11-26T18:06:25Z
dc.date2014-07-30T17:34:08Z
dc.date2015-11-26T18:06:25Z
dc.date.accessioned2018-03-29T00:48:36Z
dc.date.available2018-03-29T00:48:36Z
dc.identifierRevista Do Instituto De Medicina Tropical De Sao Paulo. Inst Medicina Tropical Sao Paulo, v. 51, n. 4, n. 203, n. 209, 2009.
dc.identifier0036-4665
dc.identifierWOS:000269527500005
dc.identifier10.1590/S0036-46652009000400005
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/66529
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/66529
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1293352
dc.descriptionExtended-spectrum beta-lactamases (ESBL) in enterobacteria are recognized worldwide as a great hospital problem. In this study, 127 ESBL-producing Enterobacteriaceae isolated in one year from inpatients and Outpatients at a public teaching hospital at Sao Paulo, Brazil, were Submitted to analysis by PCR with specific primers for bla(SHV), bla(TEM) and bla(CTX-M) genes. From the 127 isolates, 96 (75.6%) Klebsiella pneumoniae, 12 (9.3%) Escherichia coli, 8 (6.2%) Morganella morganii, 3 (2.3%) Proteus mirabilis, 2 (1.6%) Klebsiella oxytoca, 2 (1.6%) Providencia rettgeri, 2 (1.6%) Providencia stuartti, 1 (0.8%) Enterobacter aerogenes and 1 (0.8%) Enterobacter cloacae were identified as ESBL producers. Bla(SHV), bla(TEM), and bla(CTX-M) were detected in 63%, 17.3% and 33.9% strains, respectively. Pulsed field get eletrophoresis genotyping of K. pneumoniae revealed four main molecular patterns and 29 unrelated profiles. PCR results showed a high variety of ESBL groups among strains, in nine different species. The results Suggest the spread of resistance genes among genetically different strains of ESBL-producing K. pneumoniae in some hospital wards, and also that some strongly related strains were identified in different hospital wards, Suggesting clonal spread in the institutional environment.
dc.description51
dc.description4
dc.description203
dc.description209
dc.descriptionCollaborating Center of Sanitary Surveillance (CECOVISA - School of Public Health of University of Sao Paulo)
dc.languageen
dc.publisherInst Medicina Tropical Sao Paulo
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationRevista Do Instituto De Medicina Tropical De Sao Paulo
dc.relationRev. Inst. Med. Trop. Sao Paulo
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectESBL
dc.subjectEnterobacteriaceae
dc.subjectKlebsiella pneumoniae
dc.subjectPulsed Field Gel Electrophoresis
dc.subjectAntimicrobial resistance
dc.subjectKlebsiella-pneumoniae
dc.subjectPrevalence
dc.subjectEnterobactetiaceae
dc.subjectEpidemiology
dc.subjectResistance
dc.subjectSpread
dc.subjectGenes
dc.titleEXTENDED-SPECTRUM BETA-LACTAMASES AMONG Enterobacteriaceae ISOLATED IN A PUBLIC HOSPITAL IN BRAZIL
dc.typeArtículos de revistas


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