Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions

dc.creatorGoncalves, RS
dc.creatorAbdelnur, PV
dc.creatorSantos, VG
dc.creatorSimas, RC
dc.creatorEberlin, MN
dc.creatorMagalhaes, A
dc.creatorGonzalez, ERP
dc.date2011
dc.dateJAN
dc.date2014-08-01T18:27:34Z
dc.date2015-11-26T18:04:15Z
dc.date2014-08-01T18:27:34Z
dc.date2015-11-26T18:04:15Z
dc.date.accessioned2018-03-29T00:46:22Z
dc.date.available2018-03-29T00:46:22Z
dc.identifierAmino Acids. Springer, v. 40, n. 1, n. 197, n. 204, 2011.
dc.identifier0939-4451
dc.identifierWOS:000285781000018
dc.identifier10.1007/s00726-010-0634-z
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79257
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/79257
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1292800
dc.descriptionPotentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination SNAr mechanism was confirmed by NMR and MS measurements.
dc.description40
dc.description1
dc.description197
dc.description204
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationAmino Acids
dc.relationAmino Acids
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectPABA derivatives
dc.subjectLactams
dc.subjectPotential bio-activity
dc.subjectSNAr reaction
dc.subjectDerivatives
dc.subjectInhibitors
dc.subjectWater
dc.titleSynthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
dc.typeArtículos de revistas


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