Metal Nanostructures with Magnetic and Biodegradable Properties for Medical Applications

dc.creatorRuggeri, G
dc.creatorCovolan, VL
dc.creatorBernabo, M
dc.creatorLi, LM
dc.creatorValadares, LF
dc.creatorLeite, CAP
dc.creatorGalembeck, F
dc.date2013
dc.dateFEB
dc.date2014-07-30T14:01:28Z
dc.date2015-11-26T18:03:21Z
dc.date2014-07-30T14:01:28Z
dc.date2015-11-26T18:03:21Z
dc.date.accessioned2018-03-29T00:45:12Z
dc.date.available2018-03-29T00:45:12Z
dc.identifierJournal Of The Brazilian Chemical Society. Soc Brasileira Quimica, v. 24, n. 2, n. 191, n. +, 2013.
dc.identifier0103-5053
dc.identifierWOS:000317922100004
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/56575
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/56575
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1292508
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionGold nanoparticles (AuNPs) were synthesized by reduction of HAuCl4 with NaBH4 or l-ascorbic acid and they were stabilized with cysteine, cysteamine and a thiol-capped PEG. A nanocomposite was prepared by the addition of polylactic acid (PLA) acetone solutions to aqueous AuNP dispersions, resulting in PLAs enclosing AuNPs. Superparamagnetic iron oxide nanoparticles (SPION) modified with Au on the surface (SPION@Au NP) were synthesized. SPIONs were prepared by using iron-oleate as a precursor or by co-precipitation of ferrous and ferric chlorides in alkaline solution and, then used for seed-mediated growth of gold layers on their surfaces. The various nanoparticles were characterized by using UV-Vis spectroscopy, electron spectroscopy imaging/transmission electron microscopy (ESI/TEM) and by thermogravimetric analysis (TGA). The magnetic products were tested in a magnetic resonance imaging (MRI) scanner of high clinical field with results that indicate their promising utilization as contrast agents for MRI analysis.
dc.description24
dc.description2
dc.description191
dc.description+
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionUniversity of Pisa
dc.descriptionUniversity of Campinas
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.descriptionFAPESP [06-53498-2]
dc.languageen
dc.publisherSoc Brasileira Quimica
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationJournal Of The Brazilian Chemical Society
dc.relationJ. Braz. Chem. Soc.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectgold nanoparticles
dc.subjectpoly(lactic acid) (PLA)
dc.subjectbiocompatibility
dc.subjectbiocompatible polymer
dc.subjectstabilizers
dc.subjectCoated Gold Nanoparticles
dc.subjectAu Nanoparticles
dc.subjectPolymer
dc.subjectFabrication
dc.subjectAgents
dc.subjectOxide
dc.titleMetal Nanostructures with Magnetic and Biodegradable Properties for Medical Applications
dc.typeArtículos de revistas


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