Ehlers-Danlos syndrome type IV and multiple aortic aneurysms - A case report

dc.creatorMagalhaes, ED
dc.creatorFernandes, SRM
dc.creatorZanardi, VA
dc.creatorMedeiros, CAF
dc.creatorMidori, RY
dc.creatorSachetto, Z
dc.creatorSamara, AM
dc.date2001
dc.dateMAR
dc.date2014-11-19T08:13:35Z
dc.date2015-11-26T18:01:20Z
dc.date2014-11-19T08:13:35Z
dc.date2015-11-26T18:01:20Z
dc.date.accessioned2018-03-29T00:42:51Z
dc.date.available2018-03-29T00:42:51Z
dc.identifierAngiology. Westminster Publ Inc, v. 52, n. 3, n. 223, n. 228, 2001.
dc.identifier0003-3197
dc.identifierWOS:000167594900011
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/65383
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/65383
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/65383
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1291954
dc.descriptionBeside atherosclerosis, aortic aneurysms can be part of the clinical spectrum of many systemic diseases, including infectious, inflammatory, genetic and, less often, congenital disorders. A 48-year-old white man presented with multiple large aneurysms of the aorta and its main branches. Medical history was unremarkable except for the presence of a softened abdominal mass since he was 28 years old. On the physical examination, an arterial murmur was heard over the left carotid artery and a palpable mass was noted in the whole right side of the abdomen. No skin or joint abnormalities were noted. Aortography, computed tomography, and magnetic resonance angiography showed multiple large aneurysms of the descending thoracic and abdominal aorta. Aneurysms of the innominate, left subclavian, and carotid arteries were also seen. This case resembles those previously reported, in which multiple aortic aneurysms were associated with abnormalities of the type III procollagen gene (COL3A1). Although the classic stigmas of the Ehlers-Danlos syndrome type IV were lacking, this genetic disease may be the cause of the multiple aneurysms in this patient.
dc.description52
dc.description3
dc.description223
dc.description228
dc.languageen
dc.publisherWestminster Publ Inc
dc.publisherGlen Head
dc.publisherEUA
dc.relationAngiology
dc.relationAngiology
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectSingle Base Mutation
dc.subjectIii Procollagen
dc.subjectAbdominal-aorta
dc.subjectGene
dc.subjectDissection
dc.subjectCol3a1
dc.subjectInheritance
dc.subjectArteritis
dc.subjectCollagen
dc.subjectDisease
dc.titleEhlers-Danlos syndrome type IV and multiple aortic aneurysms - A case report
dc.typeArtículos de revistas


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