dc.creatorCalderini, A
dc.creatorPessine, FBT
dc.date2008
dc.dateAPR
dc.date2014-11-19T05:28:41Z
dc.date2015-11-26T17:57:49Z
dc.date2014-11-19T05:28:41Z
dc.date2015-11-26T17:57:49Z
dc.date.accessioned2018-03-29T00:41:24Z
dc.date.available2018-03-29T00:41:24Z
dc.identifierJournal Of Inclusion Phenomena And Macrocyclic Chemistry. Springer, v. 60, n. 41732, n. 369, n. 377, 2008.
dc.identifier0923-0750
dc.identifierWOS:000254457800019
dc.identifier10.1007/s10847-007-9387-z
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/74038
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/74038
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/74038
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1291588
dc.descriptionThe inclusion complex of beta-cyclodextrin and minoxidil (2,4-diamino-6-piperidinopyrimidine 3-oxide) was synthesized using two methods-kneading and freeze-drying-and characterized by UV-Vis spectroscopy, infrared spectroscopy, powder X-ray diffractometry, differential scanning calorimetry, thermal gravimetric analysis, and nuclear magnetic resonance spectroscopy. These techniques have demonstrated the existence of inclusion compound formation between the host and guest with a molar ratio of 1:1. The studies of solubility and the data obtained by nuclear magnetic resonance spectroscopy showed a weak interaction between the guest and the cyclodextrin molecules in solution.
dc.description60
dc.description41732
dc.description369
dc.description377
dc.languageen
dc.publisherSpringer
dc.publisherDordrecht
dc.publisherHolanda
dc.relationJournal Of Inclusion Phenomena And Macrocyclic Chemistry
dc.relationJ. Incl. Phenom. Macrocycl. Chem.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectminoxidil
dc.subjectbeta-cyclodextrin
dc.subjectinclusion complex
dc.subjectNMR
dc.subjectROESY
dc.subjectDOSY
dc.subjectMagnetic-resonance
dc.subjectDosage Forms
dc.subjectStability
dc.subjectWater
dc.titleSynthesis and characterization of inclusion complex of the vasodilator drug minoxidil with beta-cyclodextrin
dc.typeArtículos de revistas


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