Tissue microarray construction for salivary gland tumors study

dc.creatorPaiva-Fonseca, F
dc.creatorde-Almeida, OP
dc.creatorAyroza-Rangel, ALC
dc.creatorAgustin-Vargas, P
dc.date2013
dc.dateJAN
dc.date2014-08-01T18:22:23Z
dc.date2015-11-26T17:54:55Z
dc.date2014-08-01T18:22:23Z
dc.date2015-11-26T17:54:55Z
dc.date.accessioned2018-03-29T00:38:38Z
dc.date.available2018-03-29T00:38:38Z
dc.identifierMedicina Oral Patologia Oral Y Cirugia Bucal. Medicina Oral S L, v. 18, n. 1, n. E1, n. E6, 2013.
dc.identifier1698-4447
dc.identifierWOS:000314045500001
dc.identifier10.4317/medoral.18204
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/77946
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/77946
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1290889
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionObjective: To describe and discuss the design, building and usefulness of tissue microarray (TMA) blocks for the study of salivary gland tumors (SGTs). Study Design: Two hundred thirty-eight formalin-fixed, paraffin-embedded SGTs were arranged in blocks of TMA using a manual tissue arrayer. Three representative cores of 1.0, 2.0 or 3.0mm were taken from each original block and their characteristics were analyzed and described. Results: It was created 12 TMA blocks that presented highly representative neoplastic cylinders. However, those neoplasias rich in cystic spaces such as mucoepidermoid carcinoma and Warthin tumor presented more difficulties to be sampled, as the neoplastic tissue available was scarce. Tissue damage and loss during TMA construction was estimated as 3.7%. Conclusion: Representative areas of SGTs, with relatively small loss of tissue, can be obtained with the construction of TMA blocks for molecular studies. However, tumors rich in cystic spaces present more difficulties to be adequately sampled.
dc.description18
dc.description1
dc.descriptionE1
dc.descriptionE6
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [FAPESP 2009/53839-2]
dc.languageen
dc.publisherMedicina Oral S L
dc.publisherValencia
dc.publisherEspanha
dc.relationMedicina Oral Patologia Oral Y Cirugia Bucal
dc.relationMed. Oral Patol. Oral Cir. Bucal
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectTissue microarray
dc.subjecttma
dc.subjectsalivary gland tumors
dc.subjectimmunohistochemistry
dc.subjectAdenoid Cystic Carcinoma
dc.subjectExpression
dc.subjectTechnology
dc.subjectValidation
dc.subjectCancer
dc.subjectGeminin
dc.subjectBenign
dc.subjectSystem
dc.titleTissue microarray construction for salivary gland tumors study
dc.typeArtículos de revistas


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