Relationship among Salivary Carbonic Anhydrase VI Activity and Flow Rate, Biofilm pH and Caries in Primary Dentition

dc.creatorFrasseto, F
dc.creatorParisotto, TM
dc.creatorPeres, RCR
dc.creatorMarques, MR
dc.creatorLine, SRP
dc.creatordos Santos, MN
dc.date2012
dc.date2014-08-01T18:31:05Z
dc.date2015-11-26T17:54:53Z
dc.date2014-08-01T18:31:05Z
dc.date2015-11-26T17:54:53Z
dc.date.accessioned2018-03-29T00:38:36Z
dc.date.available2018-03-29T00:38:36Z
dc.identifierCaries Research. Karger, v. 46, n. 3, n. 194, n. 200, 2012.
dc.identifier0008-6568
dc.identifierWOS:000305109200003
dc.identifier10.1159/000337275
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/80095
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/80095
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1290883
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionThis study aimed to determine the activity of carbonic anhydrase isoenzyme VI (CAVI) in the saliva of preschool children with caries and to investigate the relationship between caries and salivary CAVI activity, salivary flow rate and biofilm pH before and after a 20% sucrose rinse. Thirty preschool children aged 45.3-80.3 months were divided into two groups: a caries-free group and a caries group. Clinical examinations were conducted by one examiner (kappa = 0.95) according to WHO criteria (dmfs) and early caries lesions. From each subject, CAVI activity, salivary flow rate and plaque pH were determined before and after a sucrose rinse. The results were submitted to Wilcoxon, Mann-Whitney and Spearman correlation tests (alpha = 0.05). The results showed that prerinse CAVI activity and its variation were higher in the saliva from caries children than from caries-free children. No difference was found between the two groups in postrinse salivary CAVI activity. After rinsing, biofilm pH differences were lower in both groups (p = 0.0012 and p = 0.0037 for the caries and caries-free groups, respectively). Also, after the sucrose rinse, salivary flow rate significantly increased in caries and caries-free groups (p = 0.0003, p = 0.0037). The variation of salivary CAVI activity was negatively correlated with caries (r = -0.501, p = 0.005). Child's age showed a positive correlation with caries (r = 0.456, p = 0.011). These results suggest that variation of salivary CAVI activity and child's age are associated with dental caries in preschool children. Copyright (C) 2012 S. Karger AG, Basel
dc.description46
dc.description3
dc.description194
dc.description200
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionFAPESP [2008/02412-6, 2008/10064-8]
dc.languageen
dc.publisherKarger
dc.publisherBasel
dc.publisherSuíça
dc.relationCaries Research
dc.relationCaries Res.
dc.rightsfechado
dc.rightshttp://www.karger.com/Services/RightsPermissions
dc.sourceWeb of Science
dc.subjectCarbonic anhydrase VI
dc.subjectPreschool children
dc.subjectPrimary dentition
dc.subjectEarly-childhood Caries
dc.subjectDental Plaque
dc.subjectBuffer Capacity
dc.subjectSugar Exposure
dc.subjectIsoenzyme Vi
dc.subjectChildren
dc.subjectExperience
dc.subjectSucrose
dc.subjectMutans
dc.titleRelationship among Salivary Carbonic Anhydrase VI Activity and Flow Rate, Biofilm pH and Caries in Primary Dentition
dc.typeArtículos de revistas


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