Effects of low laser irradiation on angiogenesis in injured rat tibiae

dc.creatorGaravello, I
dc.creatorBaranauskas, V
dc.creatorda Cruz-Hofling, MA
dc.date2004
dc.dateJAN
dc.date2014-07-30T17:21:35Z
dc.date2015-11-26T17:49:40Z
dc.date2014-07-30T17:21:35Z
dc.date2015-11-26T17:49:40Z
dc.date.accessioned2018-03-29T00:32:46Z
dc.date.available2018-03-29T00:32:46Z
dc.identifierHistology And Histopathology. F Hernandez, v. 19, n. 1, n. 43, n. 48, 2004.
dc.identifier0213-3911
dc.identifierWOS:000188355400007
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/64999
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/64999
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1289453
dc.descriptionThe influence of He-Ne laser radiation on the formation of new blood vessels in the bone marrow compartment of a regenerating area of the mid-cortical diaphysis of the tibiae of young adult rats was studied. A small hole was surgically made with a dentistry burr in the tibia and the injured area received a daily laser therapy over 7 or 14 days transcutaneously starting 24 h from surgery. Incident energy density dosages of 31.5 and 94.5 Jcm(-2) were applied during the period of the tibia wound healing investigated. Light microscopic examination of histological sections of the injured area and quantification of the newly-formed blood vessels were undertaken. Low-level energy treatment accelerated the deposition of bone matrix and histological characteristics compatible with an active recovery of the injured tissue. He-Ne laser therapy significantly increased the number of blood vessels after 7 days irradiation at an energy density of 94.5 Jcm-2, but significantly decreased the number of vessels in the 14-day irradiated tibiae, independent of the dosage. These effects were attributed to laser treatment, since no significant increase in blood vessel number was detected between 8 and 15 non-irradiated control tibiae. Molecular mechanisms involved in low-level laser therapy of angiogenesis in post-traumatic bone regeneration needs further investigation.
dc.description19
dc.description1
dc.description43
dc.description48
dc.languageen
dc.publisherF Hernandez
dc.publisherMurcia
dc.publisherEspanha
dc.relationHistology And Histopathology
dc.relationHistol. Histopath.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectangiogenesis
dc.subjectHe-Ne laser
dc.subjectbone wound healing
dc.subjecttibia
dc.subjectrat
dc.subjectHelium-neon Laser
dc.subjectLow-power Laser
dc.subjectToad Bufo-viridis
dc.subjectGastrocnemius-muscle
dc.subjectProtein-synthesis
dc.subjectIn-vitro
dc.subjectBone
dc.subjectRegeneration
dc.subjectPhotostimulation
dc.subjectEnhancement
dc.titleEffects of low laser irradiation on angiogenesis in injured rat tibiae
dc.typeArtículos de revistas


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