A pseudobiospecific hollow fiber cartridge for in vitro adsorption of autoantibodies from pathological serum

dc.creatorVentura, RCA
dc.creatorZollner, RL
dc.creatorLegallais, C
dc.creatorVijayalakshmi, MA
dc.creatorBueno, SMA
dc.date2000
dc.dateDEC
dc.date2014-07-30T13:42:38Z
dc.date2015-11-26T17:45:39Z
dc.date2014-07-30T13:42:38Z
dc.date2015-11-26T17:45:39Z
dc.date.accessioned2018-03-29T00:28:01Z
dc.date.available2018-03-29T00:28:01Z
dc.identifierBrazilian Journal Of Chemical Engineering. Brazilian Soc Chemical Eng, v. 17, n. 41824, n. 881, n. 886, 2000.
dc.identifier0104-6632
dc.identifierWOS:000165740000051
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/53641
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/53641
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1288241
dc.descriptionThe affinity filtration technique using histidine as a pseudobiospecific ligand immobilized on poly(ethylene vinyl alcohol) hollow fiber membranes (His-PEVA) was used to remove autoantibodies from serum of patients with autoimmune disease. The effects of buffering solution conditions on the efficiency of autoantibodies removal was studied. The removal of anti-dsDNA, anti-SS-A/Ro, anti-Sm, anti-Sm/RNP and anti-cardiolipin autoantibodies present in the serum was investigated, comparing the efficiency between Hepes and Tris-HCl buffers. The results showed the potential of the membrane to remove all the autoantibodies studied. Anti SS-A/Ro was removed more efficiently in Tris-HCl buffer system rather than with the Hepes buffer.
dc.description17
dc.description41824
dc.description881
dc.description886
dc.languageen
dc.publisherBrazilian Soc Chemical Eng
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationBrazilian Journal Of Chemical Engineering
dc.relationBraz. J. Chem. Eng.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectautoantibodies
dc.subjectauto-immune diseases
dc.subjectextracorporeal circulation
dc.subjecthistidine
dc.subjectaffinity membranes
dc.subjectProtein-a Immunoadsorption
dc.subjectImmunoglobulin-g
dc.subjectAntibodies
dc.subjectFiltration
dc.subjectRemoval
dc.subjectPlasma
dc.subjectIgg
dc.titleA pseudobiospecific hollow fiber cartridge for in vitro adsorption of autoantibodies from pathological serum
dc.typeArtículos de revistas


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