Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: A randomized trial

dc.creatorZanetti, FR
dc.creatorFulco, EAM
dc.creatorChaves, FRP
dc.creatorPinto, APD
dc.creatorArieta, CEL
dc.creatorLira, RPC
dc.date2012
dc.dateJUL-AUG
dc.date2014-07-30T17:09:17Z
dc.date2015-11-26T17:45:31Z
dc.date2014-07-30T17:09:17Z
dc.date2015-11-26T17:45:31Z
dc.date.accessioned2018-03-29T00:27:53Z
dc.date.available2018-03-29T00:27:53Z
dc.identifierIndian Journal Of Ophthalmology. All India Ophthalmological Soc, v. 60, n. 4, n. 277, n. 281, 2012.
dc.identifier0301-4738
dc.identifierWOS:000306856700006
dc.identifier10.4103/0301-4738.98705
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/64233
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/64233
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1288206
dc.descriptionPurpose: To compare the effects of preoperative use of topical anti-inflammatory prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery. Design: Randomized clinical trial. Materials and Methods: This single-center, masked, randomized clinical study comprised 140 patients scheduled for cataract surgery. Patients (35 in each group) were randomized to receive placebo, prednisolone acetate, ketorolac tromethamine 0.4% or nepafenac. These eye drops were administered three times daily for the two days prior to surgery. The pupillary diameters were measured by the surgeon using a compass prior to the corneal section and at the end of surgery. The primary outcome was the number of patients with pupil >= 6mm at the end of the surgery; the secondary outcome was the number of patients with pupil >= 6mm at the beginning of the surgery. Results: All the patients achieved pupil >= 6mm at the beginning of the surgery. The number of patients in the prednisolone (29/35), nepafenac (31/35) and ketorolac (30/35) groups with pupil >= 6mm was greater than in the placebo group in the maintenance of intraoperative mydriasis (19/35 - P =0.003). There was no statistical difference among the prednisolone, nepafenac and ketorolac groups in the maintenance of intraoperative mydriasis (P =. 791). There were no complications during surgery or related to the preoperative use of the eye drops. Conclusion: Preoperative use of ketorolac, prednisolone and nepafenac was effective in maintaining intraoperative mydriasis when compared with placebo.
dc.description60
dc.description4
dc.description277
dc.description281
dc.languageen
dc.publisherAll India Ophthalmological Soc
dc.publisherHyderabad
dc.publisherÍndia
dc.relationIndian Journal Of Ophthalmology
dc.relationIndian J. Ophthalmol.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectCataract
dc.subjectinflammation
dc.subjectmydriasis
dc.subjectprevention and control
dc.subjectsurgery
dc.subjectEpinephrine
dc.subjectPhacoemulsification
dc.subjectInflammation
dc.subjectPermeation
dc.subjectUtility
dc.titleEffect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: A randomized trial
dc.typeArtículos de revistas


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