Comparison of Genotypes Between Environmental and Clinical Isolates of Cryptococcus neoformans var. grubii Based on Microsatellite Patterns

dc.creatorZhu, J
dc.creatorKang, YQ
dc.creatorUno, J
dc.creatorTaguchi, H
dc.creatorLiu, Y
dc.creatorOhata, M
dc.creatorTanaka, R
dc.creatorMoretti, ML
dc.creatorMikami, Y
dc.date2010
dc.dateJAN
dc.date2014-07-30T14:00:11Z
dc.date2015-11-26T17:44:24Z
dc.date2014-07-30T14:00:11Z
dc.date2015-11-26T17:44:24Z
dc.date.accessioned2018-03-29T00:26:34Z
dc.date.available2018-03-29T00:26:34Z
dc.identifierMycopathologia. Springer, v. 169, n. 1, n. 47, n. 55, 2010.
dc.identifier0301-486X
dc.identifierWOS:000272617800005
dc.identifier10.1007/s11046-009-9230-8
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/56249
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/56249
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1287864
dc.descriptionWe applied multilocus microsatellite typing (MLMT) method to investigate the genetic relation between Cryptococcus neoformans var. grubii clinical and environmental isolates in So Paulo, Brazil. This MLMT method includes three functional gene sequences of C. neoformans var. grubii, which are dispersed on three chromosomes. In all, 89 strains (36 clinical and 53 environmental isolates) were analyzed. Of 36 clinical strains, 20 belonged to a major type of MLMT-13 (55.6%). They were mainly isolated from clinical specimens. About 52.8% of strains from the environment belong to a major type of MLMT-36, which are indigenous to environments and which were not isolated from clinical samples. Thus, we recognized two genotypes that distinguish majority of clinical and environmental strains. No differences were found in antifungal susceptibility and capsule size between major environmental and clinical MLMT types.
dc.description169
dc.description1
dc.description47
dc.description55
dc.descriptionMinistry of Education, Culture, Sports, Science and Technology of Japan
dc.languageen
dc.publisherSpringer
dc.publisherDordrecht
dc.publisherHolanda
dc.relationMycopathologia
dc.relationMycopathologia
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectCryptococcus neoformans
dc.subjectvar. grubii
dc.subjectMicrosatellite
dc.subjectClinical and environmental isolates
dc.subjectNew-york-city
dc.subjectSerotype-a
dc.subjectPigeon Droppings
dc.subjectVirulence
dc.subjectStrains
dc.subjectYeast
dc.subjectGene
dc.subjectMicroevolution
dc.subjectEpidemiology
dc.subjectPolymorphism
dc.titleComparison of Genotypes Between Environmental and Clinical Isolates of Cryptococcus neoformans var. grubii Based on Microsatellite Patterns
dc.typeArtículos de revistas


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