Does orchidopexy revert the histological alterations in epididymal and vas deferens caused by cryptorchidism?

dc.creatorArroteia, KF
dc.creatorJoazeiro, PP
dc.creatorPereira, LAV
dc.date2005
dc.dateMAR-APR
dc.date2014-07-30T14:49:24Z
dc.date2015-11-26T17:43:10Z
dc.date2014-07-30T14:49:24Z
dc.date2015-11-26T17:43:10Z
dc.date.accessioned2018-03-29T00:25:12Z
dc.date.available2018-03-29T00:25:12Z
dc.identifierArchives Of Andrology. Taylor & Francis Inc, v. 51, n. 2, n. 109, n. 119, 2005.
dc.identifier0148-5016
dc.identifierWOS:000227385200004
dc.identifier10.1080/014850190518080
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/62426
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/62426
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1287515
dc.descriptionCryptorchidism is a pathological condition in which the testicles are retained in the abdominal cavity, resulting in atrophic seminiferous tubules. Some gross structural ab-normalities and histological alterations have been described in the epididymis and vas deferens in, humans with cryptorchidic testes. Orchidopexy surgery restores testicular spermatogenesis in experimental and clinical procedures, but it is still unclear whether histological changes in the epididymis and vas deferens caused by cryptorchidism may be reverted by orchidopexy. The aim of this study was to evaluate the histological changes in the epididymis and vas deferens following experimental uni- and bilateral cryptorchidism in mature and immature mice, and to determine whether alterations could be reversed by orchidopexy. Young and adult C57 BL6 mice were randomized into three groups: control mice, bi/unilaterally cryptorchidic mice and bilaterally cryptorchidic mice with orchidopexy. After evaluation of testis, epididymis and vas deferens, there were no histological alterations in contralateral epididymis of mice unilaterally cryptorchidic. Ipsilateral epididymis of unilaterally cryptorchidic mice and epididymis from bilaterally cryptorchidic price showed significant histological alterations. Orchuidopexy restored normal spermatogenesis and the histological features of epididymis. It would appear that persistent male infertility clinically observed after orchidopexy could not be related to histological alteration, in the testis and epididymis. Development and maintenance of the vas deferens seems to be controlled independently of the epididymis since it was not altered by cryptorchidism condition.
dc.description51
dc.description2
dc.description109
dc.description119
dc.languageen
dc.publisherTaylor & Francis Inc
dc.publisherPhiladelphia
dc.publisherEUA
dc.relationArchives Of Andrology
dc.relationArch. Androl.
dc.rightsfechado
dc.rightshttp://journalauthors.tandf.co.uk/permissions/reusingOwnWork.asp
dc.sourceWeb of Science
dc.subjectcryptorchidism
dc.subjectepididymis
dc.subjectorchidopexy
dc.subjecttestis
dc.subjectvas deferns
dc.subjectUndescended Testis
dc.subjectSperm Maturation
dc.subjectDifferentiation
dc.subjectMice
dc.subjectAnomalies
dc.subjectHormone
dc.subjectRats
dc.titleDoes orchidopexy revert the histological alterations in epididymal and vas deferens caused by cryptorchidism?
dc.typeArtículos de revistas


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