Prospective and randomized comparison of electrical stimulation of the posterior tibial nerve versus oxybutynin versus their combination for treatment of women with overactive bladder syndrome

dc.creatorSouto, SC
dc.creatorReis, LO
dc.creatorPalma, T
dc.creatorPalma, P
dc.creatorDenardi, F
dc.date2014
dc.dateFEB
dc.date2014-07-30T18:08:47Z
dc.date2015-11-26T17:42:52Z
dc.date2014-07-30T18:08:47Z
dc.date2015-11-26T17:42:52Z
dc.date.accessioned2018-03-29T00:24:51Z
dc.date.available2018-03-29T00:24:51Z
dc.identifierWorld Journal Of Urology. Springer, v. 32, n. 1, n. 179, n. 184, 2014.
dc.identifier0724-4983
dc.identifier1433-8726
dc.identifierWOS:000330768300025
dc.identifier10.1007/s00345-013-1112-5
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/70572
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/70572
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1287427
dc.descriptionTo verify whether the combination of transcutaneous electrical neural stimulation (TENS) with oxybutynin in the treatment of women with overactive bladder (OAB) would be more effective than isolated treatments. We randomized 75 women with OAB, in three groups: GI-30 min TENS, twice a week; GII-daily slow release 10 mg oxybutynin; and GIII-TENS + oxybutynin (multimodal); all for 12 weeks. Patients were evaluated with validated questionnaires International Consultation on Incontinence-Short Form (ICIQ-SF), International Consultation on Incontinence-OAB (ICIQ-OAB), Symptom bother, and 3-day Voiding diary at weeks 0, 12, and 24. The groups were similar before treatment. After treatment, all groups significantly improved in OAB symptoms and quality of life (QoL). At week 12, ICIQ-OAB scores were 5.9, 4.6, and 2.9, in groups I, II, and III, respectively, p = 0.01. At week 24, GI and GIII kept the scores of the end of treatment (week 12), while GII increased ICIQ-OAB from 4.6 to 9.2, p = 0.0001, ICIQ-SF from 9.8 to 13.3, p = 0.0006, and Symptom bother score from 3.4 to 7.0, p = 0.0001. The multimodal treatment was more effective and TENS alone or in association presented longer lasting results for improvement of clinical symptoms of OAB and QoL.
dc.description32
dc.description1
dc.description179
dc.description184
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationWorld Journal Of Urology
dc.relationWorld J. Urol.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectOveractive bladder
dc.subjectAnticholinergics
dc.subjectTranscutaneous electrical neural stimulation (TENS)
dc.subjectMultimodal treatment
dc.subjectNon-drug active therapies
dc.subjectPosterior tibial nerve stimulation (PTNS)
dc.subjectSociety
dc.titleProspective and randomized comparison of electrical stimulation of the posterior tibial nerve versus oxybutynin versus their combination for treatment of women with overactive bladder syndrome
dc.typeArtículos de revistas


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