Comparative study of tissue reactivity to n-butyl-2-cyanoacrylate and nylon monofilament thread on pericranium-cutaneous flaps in rats(1)

dc.creatorCavazana, WC
dc.creatorIoshii, SO
dc.creatorCuman, RKN
dc.creatorPasseri, LA
dc.date2014
dc.dateAPR
dc.date2014-07-30T14:00:03Z
dc.date2015-11-26T17:42:40Z
dc.date2014-07-30T14:00:03Z
dc.date2015-11-26T17:42:40Z
dc.date.accessioned2018-03-29T00:24:37Z
dc.date.available2018-03-29T00:24:37Z
dc.identifierActa Cirurgica Brasileira. Acta Cirurgica Brasileira, v. 29, n. 4, n. 261, n. 267, 2014.
dc.identifier0102-8650
dc.identifier1678-2674
dc.identifierWOS:000334997000007
dc.identifier10.1590/S0102-86502014000400007
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/56170
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/56170
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1287365
dc.descriptionTo study the repair of pericranium- cutaneous flaps fixed with suture anchored in a skull bone tunnel or N-butyl-2cyanoacrylate adhesive in Wistar rats with emphasis on the cellular inflammatory response and the production of types I and III collagen. METHODS: The operated region in the cephalic region of Wistar rats was removed minutes before euthanasia, fixed in formalin, and subjected to histological preparation. Slides were stained with hematoxylin-eosin and Picrosirius. Standardized counts of polymorphonuclear and mononuclear cells, fibroblasts, and macrophages were performed, and the percentages of types I and III collagen were determined. Data collection occurred on days 3, 7, 14, 21, and 45 postoperatively. A value of p < 0.05 was considered statistically significant RESULTS: Quantitative analysis of the data showed more fibroblasts in the surgical adhesive group than in the nylon monofilament thread groups ( p= 0.0211). Qualitative analysis showed higher reactivity in the adhesive group, with a predominance of polymorphonuclear cells from days 3-45 and macrophages from days 3-7. The amount of type I collagen exceeded 80% in the treated and control groups at the end of the experiment. CONCLUSIONS: Subperiosteal detachment triggers a cellular inflammatory response that is amplified using soft tissue fixation methods. The adhesive n-butyl-2-cyanoacrylate was more reactive than the nylon monofilament thread anchored in the skull bone tunnel.
dc.description29
dc.description4
dc.description261
dc.description267
dc.languageen
dc.publisherActa Cirurgica Brasileira
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationActa Cirurgica Brasileira
dc.relationActa Cir. Bras.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectRhytidoplasty
dc.subjectCyanoacrylates
dc.subjectAdhesives
dc.subjectNylons
dc.subjectWound Healing
dc.subjectRats
dc.subjectAbdominal-wall
dc.subjectSoft-tissue
dc.subjectBrow Lift
dc.subjectCyanoacrylate
dc.subjectFixation
dc.subjectAdhesives
dc.subjectSuture
dc.subjectSurgery
dc.titleComparative study of tissue reactivity to n-butyl-2-cyanoacrylate and nylon monofilament thread on pericranium-cutaneous flaps in rats(1)
dc.typeArtículos de revistas


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