The use of hydroxyapatite and autoaenous cancellous bone grafts to repair bone defects in rats

dc.creatorSilva, RV
dc.creatorCamilli, JA
dc.creatorBertran, CA
dc.creatorMoreira, NH
dc.date2005
dc.dateMAR
dc.date2014-11-17T20:38:26Z
dc.date2015-11-26T17:42:08Z
dc.date2014-11-17T20:38:26Z
dc.date2015-11-26T17:42:08Z
dc.date.accessioned2018-03-29T00:24:00Z
dc.date.available2018-03-29T00:24:00Z
dc.identifierInternational Journal Of Oral And Maxillofacial Surgery. Churchill Livingstone, v. 34, n. 2, n. 178, n. 184, 2005.
dc.identifier0901-5027
dc.identifierWOS:000227260300013
dc.identifier10.1016/j.ijom.2004.06.005
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/72602
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/72602
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/72602
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1287207
dc.descriptionBone grafts are frequently used in the treatment of bone defects. Bone harvesting can cause postoperative complications and sometimes does not provide a sufficient quantity of bone. Therefore, synthetic biomaterials have been investigated as an alternative to autogenous bone grafts. The objective of this study was to evaluate the repair of bone defects by autogenous cancellous bone grafts or porous bioceramic discs of hydroxyapatite/phosphate cement mixture. Two 5-mm diameter defects were made in the skulls of rats and filled with the bioceramic material or cancellous bone. The rats were sacrificed 2, 4, 8 and 24 weeks after surgery and tissue samples were analyzed by radiography and histology. By the 24th week, the defects filled with autogenous cancellous bone grafts or bioceramic material showed similar volumes of bone tissue within the defect. However, defects treated with bioceramic material were almost completely closed as a result of the joining of ceramic fragments and the neoformed bone tissue, while those filled with autogenous grafts showed several areas filled with connective tissue. These results indicated that the osteointegration of bioceramic fragments allowed the reconstruction of parietal bone defects without the need for a bone graft.
dc.description34
dc.description2
dc.description178
dc.description184
dc.languageen
dc.publisherChurchill Livingstone
dc.publisherEdinburgh
dc.publisherEscócia
dc.relationInternational Journal Of Oral And Maxillofacial Surgery
dc.relationInt. J. Oral Maxillofac. Surg.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectautogenous graft
dc.subjectbone
dc.subjecthydroxyapatite
dc.subjectimplant
dc.subjectLong-term
dc.subjectCoralline Hydroxyapatite
dc.subjectImplants
dc.subjectReconstruction
dc.subjectParticles
dc.subjectIngrowth
dc.subjectSurgery
dc.subjectSystem
dc.subjectModel
dc.titleThe use of hydroxyapatite and autoaenous cancellous bone grafts to repair bone defects in rats
dc.typeArtículos de revistas


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