dc.creatorBuzalaf, MAR
dc.creatorTaga, EM
dc.creatorGranjeiro, JM
dc.creatorFerreira, CV
dc.creatorLourencao, VA
dc.creatorOrtega, MM
dc.creatorPoletto, DW
dc.creatorAoyama, H
dc.date1998
dc.dateMAY-JUN
dc.date2014-12-02T16:26:46Z
dc.date2015-11-26T17:40:41Z
dc.date2014-12-02T16:26:46Z
dc.date2015-11-26T17:40:41Z
dc.date.accessioned2018-03-29T00:22:24Z
dc.date.available2018-03-29T00:22:24Z
dc.identifierExperimental Lung Research. Hemisphere Publ Corp, v. 24, n. 3, n. 269, n. 272, 1998.
dc.identifier0190-2148
dc.identifierWOS:000074074100003
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/60968
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/60968
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/60968
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1286798
dc.descriptionProtein tyrosine phosphatase is an important Glass of enzymes that plays an essential role in the cellular proliferation, differentiation, and oncogenesis. In this paper we report characterization of a low-molecular-weight protein tyrosine phosphatase purified from bovine lung. The enzyme activity was essentially independent of metal ions and sensitive to sulfhydryl reagents. Both vanadate and inorganic phosphate are competitive inhibitors, with Ki values of 0.38 mu M and 0.28 mM, respectively. Besides p-nitrophenyl phosphate, the enzyme was also able to efficiently hydrolyze tyrosine phosphate, beta-naphthyl phosphate, and flavine mononucleotide.
dc.description24
dc.description3
dc.description269
dc.description272
dc.languageen
dc.publisherHemisphere Publ Corp
dc.publisherBristol
dc.publisherEUA
dc.relationExperimental Lung Research
dc.relationExp. Lung Res.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectbovine lung
dc.subjectkinetics
dc.subjectprotein tyrosine phosphatase
dc.subjectAcid-phosphatase
dc.subjectPurification
dc.subjectCancer
dc.subjectGene
dc.titleKinetic characterization of bovine lung low-molecular-weight protein tyrosine phosphatase
dc.typeArtículos de revistas


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