Progestin-only contraception prevents bone loss in postpartum breastfeeding women

dc.creatorCosta, ML
dc.creatorCecatti, JG
dc.creatorKrupa, FG
dc.creatorRehder, PM
dc.creatorSousa, MH
dc.creatorCosta-Paiva, L
dc.date2012
dc.dateAPR
dc.date2014-07-30T18:08:37Z
dc.date2015-11-26T17:40:40Z
dc.date2014-07-30T18:08:37Z
dc.date2015-11-26T17:40:40Z
dc.date.accessioned2018-03-29T00:22:23Z
dc.date.available2018-03-29T00:22:23Z
dc.identifierContraception. Elsevier Science Inc, v. 85, n. 4, n. 374, n. 380, 2012.
dc.identifier0010-7824
dc.identifierWOS:000301999100009
dc.identifier10.1016/j.contraception.2011.08.015
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/70476
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/70476
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1286794
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionBackground: There are an increase in bone loss during the first 6 months postpartum and a complete recovery postweaning. A few studies of steroid contraceptive use during this period provide some evidence towards protection of bone loss with progestin-only contraceptive methods. Objective: The study was conducted to evaluate forearm bone mineral density (BMD) of breastfeeding postpartum women using nonhormonal and progestin-only contraceptive methods. Study Design: A prospective cohort study of postpartum women had an analysis performed at 6 months postpartum correlating BMD with contraceptive use. Forearm BMD was measured 7-10 days, 3 months and 6 months postpartum. Eighty-two women were analyzed, comparing nonhormonal (54) and progestin-only (28) contraceptive methods. Information about breastfeeding duration, amenorrhea and body mass index was collected. Results: Baseline characteristics of the study population showed no statistical differences between the groups. The median duration of breastfeeding for both groups was 183 days. A significant BMD decrease was observed for the nonhormonal group (p<.001); however, no statistical difference was detected for the progestin-only group. Body mass index, BMD at 7-10 days postpartum and total duration of breastfeeding were positively correlated with BMD at 6 months. Conclusions: Our findings suggest a preventive effect towards postpartum bone loss with progestin-only contraception in breastfeeding women. (C) 2012 Elsevier Inc. All rights reserved.
dc.description85
dc.description4
dc.description374
dc.description380
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAEPEX/UNICAMP [421/2010]
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.descriptionFAPESP [2006/04555-3]
dc.descriptionFAEPEX/UNICAMP [421/2010]
dc.languageen
dc.publisherElsevier Science Inc
dc.publisherNew York
dc.publisherEUA
dc.relationContraception
dc.relationContraception
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectBone mineral density
dc.subjectProgestin
dc.subjectContraception
dc.subjectBreastfeeding
dc.subjectDepot-medroxyprogesterone Acetate
dc.subjectMineral Density
dc.subjectPremenopausal Women
dc.subjectLactation
dc.subjectOsteoporosis
dc.subjectForearm
dc.subjectMetaanalysis
dc.subjectPregnancy
dc.subjectHormone
dc.subjectUsers
dc.titleProgestin-only contraception prevents bone loss in postpartum breastfeeding women
dc.typeArtículos de revistas


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