Nonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation

dc.creatorCazzo, E
dc.creatorGallo, FD
dc.creatorPareja, JC
dc.creatorChaim, EA
dc.date2014
dc.dateAPR
dc.date2014-07-30T14:48:28Z
dc.date2015-11-26T17:40:31Z
dc.date2014-07-30T14:48:28Z
dc.date2015-11-26T17:40:31Z
dc.date.accessioned2018-03-29T00:22:11Z
dc.date.available2018-03-29T00:22:11Z
dc.identifierObesity Surgery. Springer, v. 24, n. 4, n. 666, n. 668, 2014.
dc.identifier0960-8923
dc.identifier1708-0428
dc.identifierWOS:000334174500027
dc.identifier10.1007/s11695-014-1183-4
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/61960
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/61960
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1286747
dc.descriptionNonalcoholic fatty liver disease (NAFLD) has become an important health issue lately. The aim of this study is to determine its prevalence among obese subjects which undergo Roux-en-Y gastric bypass (RYGB). It is a cross-sectional retrospective study involving 164 subjects who underwent RYGB. Clinical, biochemical, and histopathologic features were evaluated. The most common histopathologic features observed were steatohepatitis with fibrosis (29.9 %) and isolated fibrosis (29.3 %). Increased alkaline phosphatase was associated to NAFLD. Dyslipidemia and type 2 diabetes mellitus were associated to NAFLD. Ultrasound had a global accuracy of 78 % to detect NAFLD. Higher prevalence of severe forms of NAFLD was observed compared to previous reports. Most routine biochemical studies had poor correlation with NAFLD and ultrasound was useful but not definitive to detect NAFLD.
dc.description24
dc.description4
dc.description666
dc.description668
dc.languageen
dc.publisherSpringer
dc.publisherNew York
dc.publisherEUA
dc.relationObesity Surgery
dc.relationObes. Surg.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectFatty liver
dc.subjectObesity
dc.subjectGastric bypass
dc.subjectUltrasonography
dc.subjectLiver diseases
dc.subjectBariatric Surgery
dc.subjectGastric Bypass
dc.subjectClinical-implications
dc.subjectSteatohepatitis
dc.subjectFibrosis
dc.subjectPathophysiology
dc.subjectPrevalence
dc.subjectSteatosis
dc.subjectNash
dc.titleNonalcoholic Fatty Liver Disease in Morbidly Obese Subjects: Correlation Among Histopathologic Findings, Biochemical Features, and Ultrasound Evaluation
dc.typeArtículos de revistas


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