Artículos de revistas
A very low potential electrochemical detection of L-cysteine based on a glassy carbon electrode modified with multi-walled carbon nanotubes/gold nanorods
Registro en:
Biosensors & Bioelectronics. Elsevier Advanced Technology, v. 50, n. 202, n. 209, 2013.
0956-5663
WOS:000325188200032
10.1016/j.bios.2013.06.036
Autor
Silva, FDD
da Silva, MGA
Lima, PR
Meneghetti, MR
Kubota, LT
Goulart, MOF
Institución
Resumen
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) A nanohybrid platform built with multi-walled carbon nanotubes and gold nanorods, prepared via a cationic surfactant-containing seed-mediated sequential growth process, in aqueous solution, on a glassy carbon substrate has been successfully developed to be used in the electrocatalytic oxidation of L-cysteine (Cys). The nanohybrid was characterized by transmission electron microscopy, Raman spectroscopy and electrochemical measurements. Cyclic voltammetry results had shown that the modified electrode allows the oxidation of Cys at a very low anodic potential (0.00 V vs. Ag/AgCl). The kinetic constant k(cat) for the catalytic oxidation of Cys was evaluated by chronoamperometry and provided a value of 5.6 x 10(4) L mol(-1) s(-1). The sensor presents a linear response range from 5.0 up to 200.0 mu mol L-1, detection limit of 8.25 nmol L-1 and a sensitivity of 120 nA L mu mol(-1). (C) 2013 Elsevier B.V. All rights reserved. 50 202 209 PRONEX/FAPEAL Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) PROCAD/NF INCT-Bionalitica Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)