Hard palate hyperpigmentation secondary to chronic chloroquine therapy: report of five cases

dc.creatorde Andrade, BAB
dc.creatorFonseca, FP
dc.creatorPires, FR
dc.creatorMesquita, ATM
dc.creatorFalci, SGM
dc.creatorSilva, ARD
dc.creatorVargas, PA
dc.creatorJorge, J
dc.creatorde Almeida, OP
dc.date2013
dc.dateSEP
dc.date2014-07-30T17:52:44Z
dc.date2015-11-26T17:38:33Z
dc.date2014-07-30T17:52:44Z
dc.date2015-11-26T17:38:33Z
dc.date.accessioned2018-03-29T00:20:11Z
dc.date.available2018-03-29T00:20:11Z
dc.identifierJournal Of Cutaneous Pathology. Wiley-blackwell, v. 40, n. 9, n. 833, n. 838, 2013.
dc.identifier0303-6987
dc.identifierWOS:000323317800012
dc.identifier10.1111/cup.12182
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/68589
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/68589
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1286237
dc.descriptionAntimalarials are commonly prescribed in medical practice for conditions such as rheumatoid arthritis, lupus erythematosus, as well as malaria. They are generally well-tolerated, but side effects, although infrequent, are well known. The antimalarial chloroquine diphosphate may be associated with a bluish-gray to black hyperpigmentation of the oral mucosa, mainly on the hard palate. In this report we described five additional cases of palate hyperpigmentation related to the chronic use of chloroquine diphosphate. Professionals must be aware of the adverse effects of antimalarials as chloroquine diphosphate in order to make the correct diagnosis and appropriate management of the patient. Early diagnosis of oral pigmentation by antimalarials may be of great relevance, because it might be an early sign of ocular involvement, and therefore it may be helpful to prevent further complications of antimalarial therapy for the patient.
dc.description40
dc.description9
dc.description833
dc.description838
dc.languageen
dc.publisherWiley-blackwell
dc.publisherHoboken
dc.publisherEUA
dc.relationJournal Of Cutaneous Pathology
dc.relationJ. Cutan. Pathol.
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectadverse reaction
dc.subjectantimalarial
dc.subjectchloroquine
dc.subjecthard palate
dc.subjecthyperpigmentation
dc.subjectAdverse Drug-reactions
dc.subjectPigmentation
dc.subjectSkin
dc.titleHard palate hyperpigmentation secondary to chronic chloroquine therapy: report of five cases
dc.typeArtículos de revistas


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