Drug-related toxic events in the state of Sao Paulo, Brazil

dc.creatorGandolfi, E
dc.creatorAndrade, MDG
dc.date2006
dc.dateDEC
dc.date2014-11-16T01:24:19Z
dc.date2015-11-26T17:37:06Z
dc.date2014-11-16T01:24:19Z
dc.date2015-11-26T17:37:06Z
dc.date.accessioned2018-03-29T00:18:47Z
dc.date.available2018-03-29T00:18:47Z
dc.identifierRevista De Saude Publica. Revista De Saude Publica, v. 40, n. 6, n. 1056, n. 1064, 2006.
dc.identifier0034-8910
dc.identifierWOS:000243334700014
dc.identifier10.1590/S0034-89102006000700014
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63505
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/63505
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/63505
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1285873
dc.descriptionOBJECTIVE: To assess the epidemiological characteristics of drug-related toxic events in the State of Sao Paulo, Brazil. METHODS: A descriptive epidemiological case series study was conducted. Using the category "drug-related toxic event", 6,673 registered cases were analyzed in the Toxicology Centers in the State of Sao Paulo throughout 1998. The variables studied comprised the characteristics of the events and the affected patients, toxic agents and the circumstances involved. The analysis of toxic agents took into consideration three levels of disaggregation: herapeutical groups, active ingredients and commercial brand names. RESULTS: Drugs ranked first among all toxic agents registered in the Centers. Drug-related toxic events were mostly reported by phone (78.5%) and hospitals (86.6%); they were originated from acute oral exposure (90.2%) at home (85.7%) in the urban area (95%). Most people affected were females (59%) in their first decade of life (49.4%), mainly between two and three years of age. The most common active ingredients found were: phenobarbital, diazepam, haloperidol, carbamazepine and bromazepam. The main circumstances were accidental ingestion (38.8%) and suicidal attempts (36.5%) and among the related active ingredients, the most prevailing therapeutical group were psychiatric, analgesic/anesthetic and respiratory. CONCLUSIONS: Law-abiding practices regarding prescription drugs are needed, as well as toxicological surveillance according to the National Health System guidelines.
dc.description40
dc.description6
dc.description1056
dc.description1064
dc.languagept
dc.publisherRevista De Saude Publica
dc.publisherSao Paulo
dc.publisherBrasil
dc.relationRevista De Saude Publica
dc.relationRev. Saude Publica
dc.rightsaberto
dc.sourceWeb of Science
dc.subjectpoisoning
dc.subjectdrug toxicity
dc.subjectpharmaceutical preparations, adverse effects
dc.subjectdrug utilization
dc.subjectpoison control centers
dc.subjectinformation centers
dc.subjecthealth surveillance
dc.subjectdrugs
dc.titleDrug-related toxic events in the state of Sao Paulo, Brazil
dc.typeArtículos de revistas


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