Regio- and enantio selective reduction of methyleneketoesters mediated by Saccharomyces cerevisiae

dc.creatorClososki, GC
dc.creatorMilagre, CDF
dc.creatorMoran, PJS
dc.creatorRodrigues, JAR
dc.date2007
dc.dateSEP 24
dc.date2014-11-15T04:25:33Z
dc.date2015-11-26T17:35:56Z
dc.date2014-11-15T04:25:33Z
dc.date2015-11-26T17:35:56Z
dc.date.accessioned2018-03-29T00:18:19Z
dc.date.available2018-03-29T00:18:19Z
dc.identifierJournal Of Molecular Catalysis B-enzymatic. Elsevier Science Bv, v. 48, n. 41732, n. 70, n. 76, 2007.
dc.identifier1381-1177
dc.identifierWOS:000249373300003
dc.identifier10.1016/j.molcatb.2007.06.005
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/80391
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/80391
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/80391
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1285759
dc.descriptionMethyleneketoesters were readily prepared in high yields by performing a direct alpha-methylenation of the corresponding ketoesters using a previously described protocol. Reactions of ethyl 2-methylene-3-oxo-3-arylpropanoates 2a-c catalyzed by S. cerevisiae were performed with good conversions to give reductions of the C=C, C=O or both, depending on the reaction conditions and on the substitution of the aryl moiety. Reaction 14 of 3-methylene-2-oxo-4-phenylbutyrate 2d was carried out with free yeast cells and with yeast cells immobilized with calcium alginate, in which the major products resulted from C=C and C=O bond reduction. [GRAPHICS] (c) 2007 Elsevier B.V. All rights reserved.
dc.description48
dc.description41732
dc.description70
dc.description76
dc.languageen
dc.publisherElsevier Science Bv
dc.publisherAmsterdam
dc.publisherHolanda
dc.relationJournal Of Molecular Catalysis B-enzymatic
dc.relationJ. Mol. Catal. B-Enzym.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectFermenting Bakers-yeast
dc.subjectAlpha-methylene Ketones
dc.subjectAsymmetric Reduction
dc.subjectAlpha,beta-unsaturated Ketones
dc.subjectAbsolute-configuration
dc.subjectBiocatalysis
dc.subjectAlcohols
dc.subjectBiotransformation
dc.subjectAssignment
dc.subjectEnzymes
dc.titleRegio- and enantio selective reduction of methyleneketoesters mediated by Saccharomyces cerevisiae
dc.typeArtículos de revistas


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