Artículos de revistas
Electronically mediated selectivity in ring opening of 1-azirines. The 3-z mode: Convenient route to 2-aza-1,3-dienes
Registro en:
Journal Of Organic Chemistry. Amer Chemical Soc, v. 64, n. 1, n. 49, n. 53, 1999.
0022-3263
WOS:000077970800013
10.1021/jo980198u
Autor
Barroso, MT
Kascheres, A
Institución
Resumen
Reaction of 1-azirine-3-methylacrylates 1a,b with imidazoles and pyrazoles under mild conditions results in the formation of 2-aza-1,3-dienes 2a-g containing a potential leaving group at the 1-position. Simple alcohols (methanol and ethanol) react similarly with la,b in the presence of sodium carbonate to afford 2h-j. Utilization of 2 in the hetero Diels-Alder reaction with electron-deficient dienophiles is described. 64 1 49 53