| dc.creator | Gonzalez, MP | |
| dc.creator | Dias, LC | |
| dc.creator | Helguera, AM | |
| dc.date | 2004 | |
| dc.date | 41091 | |
| dc.date | 2014-11-16T22:33:21Z | |
| dc.date | 2015-11-26T17:27:08Z | |
| dc.date | 2014-11-16T22:33:21Z | |
| dc.date | 2015-11-26T17:27:08Z | |
| dc.date.accessioned | 2018-03-29T00:14:17Z | |
| dc.date.available | 2018-03-29T00:14:17Z | |
| dc.identifier | Polymer. Elsevier Sci Ltd, v. 45, n. 15, n. 5353, n. 5359, 2004. | |
| dc.identifier | 0032-3861 | |
| dc.identifier | WOS:000222844500037 | |
| dc.identifier | 10.1016/j.polymer.2004.04.059 | |
| dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/53928 | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/53928 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/53928 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1284723 | |
| dc.description | The topological sub-structural molecular design (TOPS-MODE) approach has been introduced for the study of mutagenic properties. The mutagenicity of 15 dental monomers was studied with this approach obtaining a good quantitative structure-toxicity model. For purposes of comparison, we employed seven different weights in the diagonal entries of the bond matrix in order to select the best TOPS-MODE model. In addition. our best model was compared with a model previously reported in the literature, and proved to be superior. Finally, the TOPS-MODE approach was used to derive the contribution of different fragments to the mutagenicity of all the compounds studied. (C) 2004 Elsevier Ltd. All rights reserved. | |
| dc.description | 45 | |
| dc.description | 15 | |
| dc.description | 5353 | |
| dc.description | 5359 | |
| dc.language | en | |
| dc.publisher | Elsevier Sci Ltd | |
| dc.publisher | Oxford | |
| dc.publisher | Inglaterra | |
| dc.relation | Polymer | |
| dc.relation | Polymer | |
| dc.rights | fechado | |
| dc.rights | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.source | Web of Science | |
| dc.subject | cycloaliphatic epoxides | |
| dc.subject | QSAR | |
| dc.subject | mutagenicity | |
| dc.subject | Edge-adjacency Matrix | |
| dc.subject | Spectral Moments | |
| dc.subject | Molecular Graphs | |
| dc.subject | Drinking-water | |
| dc.subject | Prediction | |
| dc.subject | Qsar | |
| dc.subject | Toxicology | |
| dc.subject | Toxicity | |
| dc.title | A topological sub-structural approach to the mutagenic activity in dental monomers. 2. Cycloaliphatic epoxides | |
| dc.type | Artículos de revistas | |
