Performance of the Cytologic Examination for the Diagnosis of Endocervical Adenocarcinoma in Situ Cytologic-Histologic Correlation in 60 Cases

dc.creatorZardo, LMG
dc.creatorThuler, LCS
dc.creatorZeferino, LC
dc.creatorHorta, NMSR
dc.creatorFonseca, RDSD
dc.date2009
dc.dateSEP-OCT
dc.date2014-11-16T21:13:17Z
dc.date2015-11-26T17:26:47Z
dc.date2014-11-16T21:13:17Z
dc.date2015-11-26T17:26:47Z
dc.date.accessioned2018-03-29T00:13:56Z
dc.date.available2018-03-29T00:13:56Z
dc.identifierActa Cytologica. Sci Printers & Publ Inc, v. 53, n. 5, n. 558, n. 564, 2009.
dc.identifier0001-5547
dc.identifierWOS:000269962100011
dc.identifier10.1159/000325384
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/59287
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/59287
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/59287
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1284633
dc.descriptionObjective To analyze the performance of cytologic examinations for the diagnosis of adenocarcinoma in situ (AIS) through the correlation between the cytologic and histologic findings. Study Design This study included 60 patients followed at the Brazilian National Cancer Institute from November 1998 to December 2007, with the cytopathologic diagnosis of AIS. The percentage of agreement between cytologic and histologic findings was evaluated. Results Histologic study confirmed AIS in 28.3% (17/60) and invasive endocervical adenocarcinoma in 38.3% (23/60) of the cases. In 21.7% (13/60) of the patients, the histologic examination revealed cervical intraepithelial neoplasia (CIN) 2/3 and in 5.0% (3/60) squamous invasive carcinoma; in the remaining 5.0% (3/60) the diagnosis pointed to other neoplasms, and 1.7% (1/60) showed exclusively benign squamous cell lesions. Cytology identified lesions in 98.3% of the patients; 51% was intraepithelial. Conclusion Although cytomorphologic criteria for diagnosis of AIS have been published, there was significant difficulty in interpreting glandular lesions. However, despite the fact that cytology has shown a poor performance in identifying glandular lesions, in almost all cases (98.3%) the presence of a clinically significant injury was detected. As knowledge of this diagnosis increases, better performance is expected. (Acta Cytol 2009;53:558-564)
dc.description53
dc.description5
dc.description558
dc.description564
dc.languageen
dc.publisherSci Printers & Publ Inc
dc.publisherSt Louis
dc.publisherEUA
dc.relationActa Cytologica
dc.relationActa Cytol.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectadenocarcinoma
dc.subjectPapanicolaou smear
dc.subjectuterine cervical cancer
dc.subjectAtypical Glandular Cells
dc.subjectUndetermined Significance Agus
dc.subjectUterine Cervix
dc.subjectLesions
dc.subjectSensitivity
dc.subjectCarcinoma
dc.subjectSmear
dc.subjectTests
dc.subjectWomen
dc.titlePerformance of the Cytologic Examination for the Diagnosis of Endocervical Adenocarcinoma in Situ Cytologic-Histologic Correlation in 60 Cases
dc.typeArtículos de revistas


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