dc.creatorAppenzeller, S
dc.creatorCostallat, LTL
dc.date2004
dc.dateDEC
dc.date2014-11-16T16:51:02Z
dc.date2015-11-26T17:25:53Z
dc.date2014-11-16T16:51:02Z
dc.date2015-11-26T17:25:53Z
dc.date.accessioned2018-03-29T00:13:05Z
dc.date.available2018-03-29T00:13:05Z
dc.identifierCephalalgia. Blackwell Publishing Ltd, v. 24, n. 12, n. 1024, n. 1030, 2004.
dc.identifier0333-1024
dc.identifierWOS:000225315000003
dc.identifier10.1111/j.1468-2982.2004.00785.x
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/56057
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/56057
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/56057
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1284424
dc.descriptionThe aim of this study was to determine the clinical implications of migraine in systemic lupus erythernatosus (SLE) using the cumulative organ damage scores (SLICC-DI). Eighty SLE, 40 rheumatoid arthritis (RA) patients and 40 controls (non SLE, nor RA out-patients), all women, were included. Migraine was defined according to the International Headache Society (IHS) criteria for neuropsychiatric SLE. Disease activity was measured by MEX-SLEDAI and cumulative organ damage by SLICC-DI. Statistics were obtained by Chi-square and Fischer's exact tests. ANOVA was used for comparing means. Migraine was identified in 42.5% of SLE patients, compared to 12.5% of RA patients (P < 0.05) and 10.0% (P < 0.05) in the control group. In the SLE group, a significant association between migraine and Raynaud's phenomenon (P = 0.003, OR = 10.1; 95%Cl 2.9-35) and antiphospholipid antibodies (P = 0.0012; OR = 7.5; 95%Cl 2.5-22.9) was noted. SLE patients with active migraine had higher MEX-SLEDAI scores than SLE patients without migraine. SLE patients with past history of migraine had significantly higher SLICC scores than SLE patients without migraine. History of migraine was associated with greater organ damage. Active migraine was associated with higher disease activity, antiphospholipid antibodies and worsening of Raynaud's phenomenon. The increased cumulative organ damage in SLE patients with past history of migraine justifies the routine evaluation of migraine in clinical practice.
dc.description24
dc.description12
dc.description1024
dc.description1030
dc.languageen
dc.publisherBlackwell Publishing Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationCephalalgia
dc.relationCephalalgia
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectmigraine
dc.subjectsystemic lupus erythematosus
dc.subjectcumulative organ damage
dc.subjectantiphospholipid antibodies
dc.subjectVascular Endothelial-cells
dc.subjectAntiphospholipid Antibodies
dc.subjectNeuropsychiatric Manifestations
dc.subjectBeta(2)-glycoprotein I
dc.subjectRaynauds-phenomenon
dc.subjectRecurrent Headache
dc.subjectRevised Criteria
dc.subjectDisease-activity
dc.subjectGeneral-practice
dc.subjectAssociation
dc.titleClinical implications of migraine in systemic lupus erythematosus: relation to cumulative organ damage
dc.typeArtículos de revistas


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