Protocol for volumetric segmentation of medial temporal structures using high-resolution 3-D magnetic resonance imaging

dc.creatorBonilha, L
dc.creatorKobayashi, E
dc.creatorCendes, F
dc.creatorLi, LM
dc.date2004
dc.dateJUN
dc.date2014-11-16T13:50:59Z
dc.date2015-11-26T17:25:09Z
dc.date2014-11-16T13:50:59Z
dc.date2015-11-26T17:25:09Z
dc.date.accessioned2018-03-29T00:12:26Z
dc.date.available2018-03-29T00:12:26Z
dc.identifierHuman Brain Mapping. Wiley-liss, v. 22, n. 2, n. 145, n. 154, 2004.
dc.identifier1065-9471
dc.identifierWOS:000221727100007
dc.identifier10.1002/hbm.20023
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/58351
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/58351
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/58351
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1284256
dc.descriptionQuantitative analysis of brain structures in normal subjects and in different neurological conditions can be carried out in vivo through magnetic resonance imaging (MRI) volumetric studies. The use of high-resolution MRI combined with image post-processing that allows simultaneous multiplanar view may facilitate volumetric segmentation of temporal lobe structures. We define a protocol for volumetric studies of medial temporal lobe structures using high-resolution MR images and we studied 30 healthy subjects (19 women; mean age, 33 years; age range, 21-55 years). Images underwent field non-homogeneity correction and linear stereotaxic transformation into a standard space. Structures of interest comprised temporopolar, entorhinal, perirhinal, parahippocampal cortices, hippocampus, and the amygdala. Segmentation was carried out with multiplanar assessment. There was no statistically significant left/right-sided asymmetry concerning any structure analyzed. Neither gender nor age influenced the volumes obtained. The coefficient of repeatability showed no significant difference of intra- and interobserver measurements. Imaging post-processing and simultaneous multiplanar view of high-resolution MRI facilitates volumetric assessment of the medial portion of the temporal lobe with strict adherence to anatomic landmarks. This protocol shows no significant inter- and intraobserver variations and thus is reliable for longitudinal studies. (C) 2004 Wiley-Liss, Inc.
dc.description22
dc.description2
dc.description145
dc.description154
dc.languageen
dc.publisherWiley-liss
dc.publisherHoboken
dc.publisherEUA
dc.relationHuman Brain Mapping
dc.relationHum. Brain Mapp.
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectmagnetic resonance image
dc.subjecttemporal lobe
dc.subjectparahippocampal gyrus
dc.subjectvolumetric analysis
dc.subjectEntorhinal Cortex
dc.subjectLobe Epilepsy
dc.subjectHippocampal Sclerosis
dc.subjectMorphometric-analysis
dc.subjectHuman Amnesia
dc.subjectGray-matter
dc.subjectHuman Brain
dc.subjectMr Images
dc.subjectMemory
dc.subjectAmygdala
dc.titleProtocol for volumetric segmentation of medial temporal structures using high-resolution 3-D magnetic resonance imaging
dc.typeArtículos de revistas


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