The influence of preparation conditions on the characteristics of chitosan-alginate dressings for skin lesions

dc.creatorRodrigues, AP
dc.creatorSanchez, EMS
dc.creatorda Costa, AC
dc.creatorMoraes, AM
dc.date2008
dc.dateAUG 15
dc.date2014-11-16T04:24:09Z
dc.date2015-11-26T17:23:10Z
dc.date2014-11-16T04:24:09Z
dc.date2015-11-26T17:23:10Z
dc.date.accessioned2018-03-29T00:10:31Z
dc.date.available2018-03-29T00:10:31Z
dc.identifierJournal Of Applied Polymer Science. John Wiley & Sons Inc, v. 109, n. 4, n. 2703, n. 2710, 2008.
dc.identifier0021-8995
dc.identifierWOS:000256847500078
dc.identifier10.1002/app.28203
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/73498
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/73498
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/73498
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1283765
dc.descriptionIn this work, the preparation and characterization of membranes obtained through chitosan and alginate coacervation and designed for use as wound dressings were evaluated. The influence of different stirring rates and rates of addition of chitosan solution to alginate solution on the final characteristics of the biomaterial was analyzed in detail, aiming at a simple and easily scalable membrane production protocol. The results show that membranes with dry thickness from 66 to 80 pm, wet thickness from 106 to 633 mu m, tensile strength varying from 6.86 to 31.14 MPa, elongation at break from 3.97 to 8.42%, and maximum water uptake up to 19 g of water per gram of membrane and that are able to prevent the permeation of bacteria can be obtained in a fairly reproducible way by the procedure established. The membranes prepared at flow ratio of 40 mL/h and stirring equal to 100 rpm showed a high potential for use on highly exuding wounds. (c) 2008 Wiley Periodicals, Inc.
dc.description109
dc.description4
dc.description2703
dc.description2710
dc.languageen
dc.publisherJohn Wiley & Sons Inc
dc.publisherHoboken
dc.publisherEUA
dc.relationJournal Of Applied Polymer Science
dc.relationJ. Appl. Polym. Sci.
dc.rightsfechado
dc.rightshttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dc.sourceWeb of Science
dc.subjectmembranes
dc.subjectbiomaterials
dc.subjectpolyelectrolytes
dc.subjecthydrogels
dc.subjectmechanical properties
dc.subjectchitosan
dc.subjectalginate
dc.subjectwound dressing
dc.subjectcoacervates
dc.subjectMechanical-properties
dc.subjectWound Dressings
dc.subjectMembranes
dc.subjectFabrication
dc.subjectFilms
dc.titleThe influence of preparation conditions on the characteristics of chitosan-alginate dressings for skin lesions
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución