Frequencies of platelet-specific alloantigen systems 1-5 in three distinct ethnic groups in Brazil

dc.creatorCastro, V
dc.creatorOriga, AF
dc.creatorAnnichino-Bizzacchi, JM
dc.creatorSoares, M
dc.creatorMenezes, RC
dc.creatorGoncalves, MS
dc.creatorCosta, FF
dc.creatorArruda, VR
dc.date1999
dc.dateOCT
dc.date2014-12-02T16:25:10Z
dc.date2015-11-26T17:21:08Z
dc.date2014-12-02T16:25:10Z
dc.date2015-11-26T17:21:08Z
dc.date.accessioned2018-03-29T00:08:40Z
dc.date.available2018-03-29T00:08:40Z
dc.identifierEuropean Journal Of Immunogenetics. Blackwell Science Ltd, v. 26, n. 5, n. 355, n. 360, 1999.
dc.identifier0960-7420
dc.identifierWOS:000083338400007
dc.identifier10.1046/j.1365-2370.1999.00174.x
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/67163
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/67163
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/67163
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1283296
dc.descriptionThe human platelet antigen (HPA) systems are related to immune platelet disorders as well as to the development of occlusive vascular disease. Several distinct biallelic HPA systems are known, and a heterogeneous distribution of HPA alleles has been described among distinct ethnic groups. In this study we genotyped 320 carefully selected individuals from three distinct ethnic groups in Brazil (Caucasians, Blacks and Amazonian Indians) for the HPA-1, -2, -3, -4 and -5 systems. A similar prevalence for all HPA alleles was found in Brazilians of Caucasian and Black descent. These data contrast with those reported for similar ethnic groups in other countries. Among the Amazonian Indians, no b allele of the HPA-1, -4 and -5 systems was identified. The data presented here could be useful in the diagnosis of alloimmune platelet disease, in genetic counselling and in the development of screening programmes for HPA-related diseases.
dc.description26
dc.description5
dc.description355
dc.description360
dc.languageen
dc.publisherBlackwell Science Ltd
dc.publisherOxford
dc.publisherInglaterra
dc.relationEuropean Journal Of Immunogenetics
dc.relationEur. J. Immunogenet.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectNeonatal Alloimmune Thrombocytopenia
dc.subjectGlycoprotein-iiia
dc.subjectGene-frequencies
dc.subjectVenous Thrombosis
dc.subjectPolymorphism
dc.subjectAntigens
dc.subjectPopulation
dc.subjectDisease
dc.subjectDna
dc.subjectPrevalence
dc.titleFrequencies of platelet-specific alloantigen systems 1-5 in three distinct ethnic groups in Brazil
dc.typeArtículos de revistas


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