The impact of pregnancy and childbirth in the urethra of female rats

dc.creatorRocha, MA
dc.creatorSartori, MGF
dc.creatorSimoes, MD
dc.creatorHerrmann, V
dc.creatorBaracat, EC
dc.creatorde Lima, GR
dc.creatorGirao, MJBC
dc.date2007
dc.dateJUN
dc.date2014-11-14T23:11:14Z
dc.date2015-11-26T17:17:46Z
dc.date2014-11-14T23:11:14Z
dc.date2015-11-26T17:17:46Z
dc.date.accessioned2018-03-29T00:05:37Z
dc.date.available2018-03-29T00:05:37Z
dc.identifierInternational Urogynecology Journal. Springer London Ltd, v. 18, n. 6, n. 645, n. 651, 2007.
dc.identifier0937-3462
dc.identifierWOS:000247005600011
dc.identifier10.1007/s00192-006-0221-8
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/73747
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/73747
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/73747
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1282527
dc.descriptionThe aim of this study was to evaluate the modifications in the amount of collagen, muscular, and elastic fibers in the mid-urethra of adult female rats during the pregnancy and after the natural childbirth, cesarean, and after simulated trauma of childbirth. The authors evaluated the histomorphometric aspects (collagen, muscular, and elastic fibers) in the mid.-urethra of 70 animals distributed in seven groups: group 1 (n=10)-control, group 2 (n=10)pregnant female rats, group 3 (n=10)-female rats submitted to cesarean, group 4 (n=10)-female rats with natural childbirth, group 5 (n=10)-virgin female rats with simulated trauma of childbirth, group 6 (n=10)-female rats submitted to cesarean followed by simulation of childbirth trauma, and group 7 (n=10)-female rats with natural childbirth followed by simulation of childbirth trauma. The average concentration of collagen and elastic fibers and the collagen/muscular fiber correlation in groups 1, 2, and 3 were similar and significantly inferior to groups 4, 5, 6, and 7. The average of muscular fibers was similar in groups 1, 2, and 3 and significantly superior to groups 4, 5, 6, and 7. Pregnancy and cesarean did not induce alterations in collagen, muscular, and elastic fibers. However, the vaginal delivery and simulation of childbirth trauma determined the decrease in muscular fibers and the increase in collagen and elastic fibers and the correlation collagen/ muscular fiber.
dc.description18
dc.description6
dc.description645
dc.description651
dc.languageen
dc.publisherSpringer London Ltd
dc.publisherArtington
dc.publisherInglaterra
dc.relationInternational Urogynecology Journal
dc.relationInt. Urogynecol. J.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectpregnancy
dc.subjecttrauma of childbirth
dc.subjectcollagen
dc.subjectmuscular fiber
dc.subjectStress-incontinence
dc.subjectPelvic-floor
dc.subjectUrinary-incontinence
dc.subjectElastic Fiber
dc.subjectWomen
dc.subjectCollagen
dc.subjectDamage
dc.subjectAge
dc.titleThe impact of pregnancy and childbirth in the urethra of female rats
dc.typeArtículos de revistas


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