Cariogenic potential of cows', human and infant formula milks and effect of fluoride supplementation

dc.creatorPeres, RCR
dc.creatorCoppi, LC
dc.creatorVolpato, MC
dc.creatorGroppo, FC
dc.creatorCury, JA
dc.creatorRosalen, PL
dc.date2009
dc.dateFEB 14
dc.date2014-11-14T18:54:35Z
dc.date2015-11-26T17:16:14Z
dc.date2014-11-14T18:54:35Z
dc.date2015-11-26T17:16:14Z
dc.date.accessioned2018-03-29T00:04:25Z
dc.date.available2018-03-29T00:04:25Z
dc.identifierBritish Journal Of Nutrition. Cambridge Univ Press, v. 101, n. 3, n. 376, n. 382, 2009.
dc.identifier0007-1145
dc.identifierWOS:000263093400010
dc.identifier10.1017/S0007114508020734
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/63183
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/63183
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/63183
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1282234
dc.descriptionThe aim of the present study was to evaluate the cariogenicity of cows', human and infant formula milks, supplemented or not with fluoride, in rats. Sixty female Wistar rats were desalivated and infected with Streptococcus sobrinus 6715. Animals were divided into six groups: group 1, sterilised deionised distilled water (SDW; negative control); group 2, 5 % sucrose added to SDW (positive control); group 3, human milk; group 4, cows' milk; group 5, Ninho (R) formula reconstituted with SDW; group 6, Ninho (R) formula reconstituted with 10 parts per million F and SDW. At day 21 the animals were killed and their jaws removed to quantify total cultivable microbiota, Strep. sobrinus and dental caries. The concentration of carbohydrate and fluoride in the milks was analysed. The Kruskal-Wallis test (alpha = 5 %) was used to analyse the data. The caries score by the milk formula was as high as that provoked by sucrose. Regarding smooth-surface caries, human milk was statistically more cariogenic than cows' milk, which did not differ from the SDW and the Ninho (R) with fluoride (P>0.05). Groups 2-6 showed higher Strep. sobrinus counts when compared with the negative control group (P<0-05) but no statistically significant difference was found among them (P>0.05). HPLC analysis showed that infant formula had 9.3 % sucrose and 3-6 % reducing sugars. The infant formula should be considered cariogenic due to the sugars found in it, but fluoride supplementation reduced its cariogenic effect. The human milk was more cariogenic than the cows' milk but not as much as the formula milk.
dc.descriptiono TEXTO COMPLETO DESTE ARTIGO, ESTARÁ DISPONÍVEL À PARTIR DE AGOSTO DE 2015.
dc.description101
dc.description3
dc.description376
dc.description382
dc.languageen
dc.publisherCambridge Univ Press
dc.publisherCambridge
dc.publisherInglaterra
dc.relationBritish Journal Of Nutrition
dc.relationBr. J. Nutr.
dc.rightsembargo
dc.rightshttp://journals.cambridge.org/action/displaySpecialPage?pageId=4676
dc.sourceWeb of Science
dc.subjectCaries
dc.subjectCommercial milk formula
dc.subjectRats
dc.subjectEarly-childhood Caries
dc.subjectDental-caries
dc.subjectDesalivated Rats
dc.subjectPrimary Teeth
dc.subjectIn-vitro
dc.subjectChildren
dc.subjectPrevalence
dc.subjectFluorosis
dc.subjectSucrose
dc.subjectLactose
dc.titleCariogenic potential of cows', human and infant formula milks and effect of fluoride supplementation
dc.typeArtículos de revistas


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