Artículos de revistas
Probing the stereoselectivity of the Heck arylation of endocyclic enecarbarnates with diazonium salts. Concise syntheses of (2S,5R)-phenylproline methyl ester and Schramm's C-azanucleoside
Registro en:
Organic Letters. Amer Chemical Soc, v. 5, n. 3, n. 305, n. 308, 2003.
1523-7060
WOS:000180766400019
10.1021/ol027268a
Autor
Severino, EA
Costenaro, ER
Garcia, ALL
Correia, CRD
Institución
Resumen
[GRAPHICS] The diastereoselectivity of the Heck arylation of several chiral, nonracemic, five-membered endocyclic enecarbamates with aryldiazonium tetrafluoroborates was evaluated. The cis selectivity observed for some enecarbamates bearing coordinating groups was explored in the concise synthesis of the (2S,5R)-(+)-phenylproline methyl ester, a scaffold for the nonpeptide cholecystokinin antagonist (+)-RP 66803, and in the synthesis of Schramm's potent antiprotozoan C-azanucleoside. 5 3 305 308