Value of extent of hippocampal resection in the surgical treatment of temporal lobe epilepsy

dc.creatorBonilha, L
dc.creatorKobayashi, E
dc.creatorMattos, JPV
dc.creatorHonorato, DC
dc.creatorLi, LM
dc.creatorCendes, F
dc.date2004
dc.dateMAR
dc.date2014-11-20T04:26:17Z
dc.date2015-11-26T17:14:08Z
dc.date2014-11-20T04:26:17Z
dc.date2015-11-26T17:14:08Z
dc.date.accessioned2018-03-29T00:02:27Z
dc.date.available2018-03-29T00:02:27Z
dc.identifierArquivos De Neuro-psiquiatria. Assoc Arquivos De Neuro- Psiquiatria, v. 62, n. 1, n. 15, n. 20, 2004.
dc.identifier0004-282X
dc.identifierWOS:000220722200003
dc.identifier10.1590/S0004-282X2004000100003
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/73158
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/73158
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/73158
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1281737
dc.descriptionObjective: Unilateral hippocampal atrophy is indicator of good surgical prognosis in patients with temporal lobe epilepsy (TLE). Some patients however do not become seizure free after surgery. We assessed if the extent of hippocampal and amygdala resection is associated with outcome. Methods: Thirty patients with TLE with unilateral or clearly asymmetric hippocampal atrophy who underwent surgical treatment were evaluated concerning preoperative clinical variables and interictal EEG abnormalities. Amygdala and hippocampal resection was evaluated by post-operative MRI. We compared seizure free versus non-seizure free patients, and patients with good outcome (Engel's classes I and II) versus patients with poor outcome, Results: There was significant association between the extent of hippocampal resection and the outcome. Pre-operative variables and interictal EEG abnormalities did not show relationship with outcome as documented in previous studies. Conclusion: The extent of hippocampal resection is associated with outcome. Incomplete resection of atrophic hippocampus may explain most surgical failures in patients with TLE due to unilateral hippocampal sclerosis.
dc.description62
dc.description1
dc.description15
dc.description20
dc.languageen
dc.publisherAssoc Arquivos De Neuro- Psiquiatria
dc.publisherSao Paulo Sp
dc.publisherBrasil
dc.relationArquivos De Neuro-psiquiatria
dc.relationArq. Neuro-Psiquiatr.
dc.rightsaberto
dc.sourceWeb of Science
dc.subjecttemporal lobe epilepsy
dc.subjectepilepsy surgery
dc.subjectinterictal EEG
dc.subjectLobectomy
dc.subjectMri
dc.subjectSeizures
dc.subjectSurgery
dc.subjectAtrophy
dc.subjectEeg
dc.titleValue of extent of hippocampal resection in the surgical treatment of temporal lobe epilepsy
dc.typeArtículos de revistas


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