Artículos de revistas
A new entry to the synthesis of substituted azetidines: [2+2] cycloaddition reaction of four-membered endocyclic enamides to ketenes
Registro en:
Tetrahedron Letters. Pergamon-elsevier Science Ltd, v. 47, n. 36, n. 6377, n. 6380, 2006.
0040-4039
WOS:000240090200011
10.1016/j.tetlet.2006.06.174
Autor
Burtoloso, ACB
Correia, CRD
Institución
Resumen
The first example of a [2+2] cycloaddition reaction of a four-membered endocyclic enamide (2-azetine) to dichloroketene is described and constitutes a new entry to the synthesis of substituted azetidines. Preliminary studies concerning the Baeyer Villiger oxidation of the [2+2] cycloadduct revealed an unusual regioselectivity. The synthesis of a new azetidine-3-carboxylic acid derivative from the [2+2] cycloadduct is also presented. (c) 2006 Elsevier Ltd. All rights reserved. 47 36 6377 6380