Preoperative pelvic lymphoscintigraphy is of limited usefulness for sentinel lymph node detection in cervical cancer

dc.creatorVieira, SC
dc.creatorSousa, RB
dc.creatorTavares, MBAC
dc.creatorSilva, JB
dc.creatorAbreu, BAL
dc.creatorSantos, LG
dc.creatorda Silva, BB
dc.creatorZeferino, LC
dc.date2009
dc.dateJUL
dc.date2014-11-13T15:20:42Z
dc.date2015-11-26T17:10:07Z
dc.date2014-11-13T15:20:42Z
dc.date2015-11-26T17:10:07Z
dc.date.accessioned2018-03-28T23:58:43Z
dc.date.available2018-03-28T23:58:43Z
dc.identifierEuropean Journal Of Obstetrics & Gynecology And Reproductive Biology. Elsevier Ireland Ltd, v. 145, n. 1, n. 96, n. 99, 2009.
dc.identifier0301-2115
dc.identifierWOS:000268439400020
dc.identifier10.1016/j.ejogrb.2009.03.025
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/70081
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/70081
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/70081
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1280785
dc.descriptionObjectives: To analyze concordance between preoperative lymphoscintigraphy and intraoperative lymphatic mapping (ILM) for sentinel lymph node identification using technetium 99m-labeled-dextran 500 (99m-Tc) and patent blue dye in patients with early cervical cancer undergoing radical hysterectomy and pelvic lymphadenectomy, as well as to evaluate sentinel lymph node (SLN) detection. Study design: Forty-seven patients underwent surgical treatment for cervical cancer. For SLN identification, 99m-Tc and blue patent were injected into the cervix on the eve and day of surgery, respectively. Preoperative pelvic lymphoscintigraphy was performed in all patients after 99m-Tc injection. Concordance between preoperative lymphoscintigraphy and ILM was evaluated. Results: Of the 56 patients who underwent preoperative lymphoscintigraphy, 43 (81.13%) had at least one lymph node identified. Bilateral lymph nodes were identified in 21 (37.5%) patients. Sentinel lymph nodes detected on ILM had been previously found on preoperative lymphoscintigraphy in 66.7%, 67.2% and 0% in the right, left and central locations, respectively. In 14 patients (25%), only one lymph node was identified on preoperative lymphoscintigraphy, but more than one sentinel lymph node was detected on intraoperative mapping. In nine (16.1%) patients, lymphoscintigraphy showed only unilateral lymph nodes, but ILM identified bilateral sentinel lymph nodes. Conclusion: The combination of patent blue and radionuclide techniques produced excellent results for SLN detection in cervical cancer. Preoperative lymphoscintigraphy does not offer any advantage over ILM for SLN identification. (c) 2009 Elsevier Ireland Ltd. Ail rights reserved.
dc.description145
dc.description1
dc.description96
dc.description99
dc.languageen
dc.publisherElsevier Ireland Ltd
dc.publisherClare
dc.publisherIrlanda
dc.relationEuropean Journal Of Obstetrics & Gynecology And Reproductive Biology
dc.relationEur. J. Obstet. Gynecol. Reprod. Biol.
dc.rightsfechado
dc.rightshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.sourceWeb of Science
dc.subjectCervical cancer
dc.subjectLymphoscintigraphy
dc.subjectSentinel lymph node
dc.subjectPatent blue dye
dc.subjectRadionuclide
dc.subjectLymphadenectomy
dc.subjectWomen
dc.subjectBlue
dc.titlePreoperative pelvic lymphoscintigraphy is of limited usefulness for sentinel lymph node detection in cervical cancer
dc.typeArtículos de revistas


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