Artículos de revistas
On 1,4-diastereoselectivity in the chiral allylsilane addition to chiral alpha-substituted aldehydes
Registro en:
Tetrahedron Letters. Pergamon-elsevier Science Ltd, v. 39, n. 30, n. 5343, n. 5346, 1998.
0040-4039
WOS:000074562000015
10.1016/S0040-4039(98)01066-1
Autor
Dias, LC
Giacomini, R
Institución
Resumen
Chiral allylsilane 2 reacted with chiral alpha-substituted aldehydes to afford the corresponding 1,4-syn-products with good diastereoselectivities. The best selectivities are observed when the reactions are carried out by transmetallation of allylsilane using Tin (IV) chloride in CH2Cl2, at -78 degrees C, before addition of the aldehydes. (C) 1998 Elsevier Science Ltd. All rights reserved. 39 30 5343 5346